Results 51 to 60 of about 65,822 (289)

Large schwannoma of the sciatic nerve [PDF]

BMJ Case Reports, 2016
A 40-year-old woman was referred with an 8-month history of fullness of the right posterior thigh. This was associated with pain, primarily on sitting and occasional radicular pain down the ipsilateral leg. On examination a mobile, firm lump was identified that was tender to palpate and which also elicited a shooting pain down the leg on examination ...
Owen, Godkin, Prasad, Ellanti, Gary, O'Toole   +2 more
openaire   +2 more sources

Nerve stimulator-guided sciatic-femoral nerve block in raptors undergoing surgical treatment of pododermatitis.

, 2014
OBJECTIVE To describe the nerve stimulator-guided sciatic-femoral nerve block in raptors undergoing surgical treatment of pododermatitis. STUDY DESIGN Prospective clinical trial. ANIMALS Five captive raptors (Falco peregrinus) aged 6.7 ± 1.
Noviello, E, Noviello, Emilio, D'Ovidio, D, d'Ovidio, Dario, Adami, C, Adami, Chiara   +5 more
core   +1 more source

Depletion of p75NTR in Schwann Cells Driven by Inflammation Mediates Cutaneous Pain in Psoriasis

Advanced Science, EarlyView.
Psoriasis‐like inflammation induces proliferation and molecular remodeling of cutaneous Schwann cells, marked by reduced p75NTR and increased NGF expression. IL‐17A promotes this process, whereas Schwann cell‐specific p75NTR overexpression alleviates cutaneous pain in vivo.
Yibo Wang, Linlin Xu, Chenglong Pan, Ruonan Cao, Piao Zeng, Xinxing Lyu, Qingxia Hu, Zhenzhen Yan, Shuhong Huang, Ningning Dang   +9 more
wiley   +1 more source

Enhancement of sciatic nerve regeneration with dual delivery of vascular endothelial growth factor and nerve growth factor genes

Journal of Nanobiotechnology, 2020
Background Peripheral nerve injury is one common clinical disease worldwide, in which sciatic nerve is anatomically the most challenging to regenerate given its length and large cross-sectional area.
Zhiwei Fang, Xuemei Ge, Xuan Chen, Yang Xu, Wei-En Yuan, Yuanming Ouyang   +5 more
doaj   +1 more source

Divergent Roles of mGlu2 and mGlu3 Receptors in Amyloid‐β Production and Cognitive Dysfunctions in Alzheimer's Disease

Advanced Science, EarlyView.
This study explores the opposing effects of the mGluR2 and mGluR3 receptors on amyloid precursor protein processing. mGluR2 promotes amyloidogenic cleavage, while mGluR3 favors non‐amyloidogenic pathways. Using a brain‐penetrant nanobody as a mGluR2 positive allosteric modulator, the study uncovers how its chronic activation aggravates amyloid‐β burden
Pierre‐André Lafon, Mireille Elodie Tsitokana, Ugo Guy Alenda, Yen‐Ling Lian, Clémentine Eva Philibert, Mathieu Oosterlaken, Marta Cimadevila, Gaëlle Dudon, Jessica Monnic, Salomé Roux, Julie Bessié, Séverine Diem, Franck Vandermoere, Laurent Prézeau, Patrick Chames, Julie Kniazeff, Sylvie Claeysen, Anaïs Menny, Jean‐Philippe Pin, Véronique Perrier, Jianfeng Liu, Philippe Rondard   +21 more
wiley   +1 more source

Reunification of a split sciatic nerve

Anatomy & Cell Biology, 2020
Sciatic nerve (SN) variaitons can result in interesting clinical presentations. We identified a SN variant that does not fit into preexisting classification schemes. In an adult male cadaver, the SN was found to divide proximally and partly exit through the piriformis muscle. Distal to the piriformis, the two parts of the SN were reunited.
Brendan Huang, Tess Decater, Joe Iwanaga, Aaron S. Dumont, R. Shane Tubbs   +4 more
openaire   +3 more sources

Spontaneous Non‐Catalyzed Molecular Reactions and Interactions in the Human Body: Biomedical Implications

Advanced Science, EarlyView.
ABSTRACT The human body functions as a natural reactor for a vast network of chemical and biological reactions and physical interactions among small molecules, proteins, cells, and numerous other components. These reactions/interactions are essential for maintaining normal physiological functions.
Yuhao Cai, Chao Zhao
wiley   +1 more source

High division of the Sciatic Nerve: A case study for an anatomical variation and clinical significance [PDF]

Journal of Nursing Advances in Clinical Sciences
During a routine dissection for first-year MBBS students at the Department of Anatomy, JSS Medical College, we found a bilateral variation of the sciatic nerve in the gluteal region. The variations were noted and photographed. Further, its anatomical and
Arigela Saikumar, Shwetha. K, Vidya C.S
doaj   +1 more source

Continuous sciatic nerve block [PDF]

Anaesthesia, 1984
Summary A technique of continuous sciatic nerve block is described. The method was used to relieve pain from ischaemic gangrene of the foot for 2 days before below‐knee amputation and, combined with a continuous inguinal paravascular block, to provide regional anaesthesia both for the surgery and for the first 2 postoperative days.
B E, Smith, H B, Fischer, P V, Scott
openaire   +2 more sources

Sciatic Nerve Block Combined with Flurbiprofen Inhibits Spinal Cord Inflammation and Improves Postoperative Pain in Rats with Plantar Incision

, 2023
Meihong Li,1 Kaiwen Zhang,1 Ting Li,2 Yuye Chen,1 Hu Zang,1 Yingjie Hu,1 Wenlong Yao1 1Hubei Key Laboratory of Geriatric Anesthesia and Perioperative Brain Health, and Wuhan Clinical Research Center for Geriatric Anesthesia, Department of Anesthesiology,
Zhang K, Hu Y, Li T, Zang H, Chen Y, Yao W, Li M   +6 more
core