Efficacy of continuous catheter analgesia of the sciatic nerve after total knee arthroplasty
PURPOSE: This study investigated and compared the outcomes after continuous femoral nerve block alone, continuous femoral nerve analgesia combined with single-shot sciatic nerve analgesia, and continuous femoral and sciatic nerve analgesia in ...
Jan P. Benthien, Dietrich Huebner
doaj +1 more source
Denervated Schwann cells attract macrophages by secretion of leukemia inhibitory factor (LIF) and monocyte chemoattractant protein-1 in a process regulated by interleukin-6 and LIF [PDF]
Injury to peripheral nerves results in the infiltration of immune cells, which remove axonal- and myelin-derived material. Schwann cells could play a key role in this process by regulating macrophage infiltration.
Jessen, KR +3 more
core +2 more sources
Effect of intravenous dexamethasone on the duration of postoperative analgesia for popliteal sciatic nerve block: a randomized, double-blind, placebo-controlled study [PDF]
Background Intravenous (IV) dexamethasone prolongs the duration of a peripheral nerve block; however, there is little available information about its optimal effective dose.
Byung-Gun Kim +5 more
doaj +1 more source
A comparison of epidural anesthesia and lumbar plexus-sciatic nerve blocks for knee surgery
OBJECTIVES: The efficacy of combined lumbar plexus-sciatic nerve blocks was compared to epidural anesthesia in patients undergoing total knee surgery. PATIENTS AND METHODS: The study included 80 American Society of Anesthesiologists (ASA) Physical Status
Eyup Horasanli +5 more
doaj +1 more source
Acute- and late-phase matrix metalloproteinase (MMP)-9 activity is comparable in female and male rats after peripheral nerve injury. [PDF]
BACKGROUND:In the peripheral nerve, pro-inflammatory matrix metalloproteinase (MMP)-9 performs essential functions in the acute response to injury. Whether MMP-9 activity contributes to late-phase injury or whether MMP-9 expression or activity after ...
Angert, Mila +6 more
core +2 more sources
The NMDA receptor functions independently and as an LRP1 co-receptor to promote Schwann cell survival and migration [PDF]
NMDA Receptors (NMDA-Rs) are ionotropic glutamate receptors, which associate with LDL Receptor-related Protein-1 (LRP1) to trigger cell-signaling in response to protein ligands in neurons.
Campana, W. Marie +4 more
core +2 more sources
Background: Peripheral nerve blocks (PNBs) are generally used to provide postoperative analgesia after total knee arthroplasty (TKA) and other lower extremity procedures; these blocks are used rarely for intraoperative anesthesia.
Sangeeta Khanna +3 more
doaj +1 more source
Background: This study aimed to evaluate the impact of Infiltration between the Popliteal Artery and Capsule of the posterior Knee (IPACK) combined with an adductor canal block under the guidance of ultrasound on early motor function after Total Knee ...
Fang-Yu Zheng +6 more
doaj +1 more source
Activity of Cyclic AMP Phosphodiesterases and Adenylyl Cyclase in Peripheral Nerve after Crush and Permanent Transection Injuries [PDF]
Recent studies demonstrate that cAMP levels are tightly controlled during demyelination and remyelination in Schwann cells as cAMP decreases to 8–10% of normal following both sciatic nerve crush or permanent transection injury and only begins to increase
Poduslo, Joseph F. +1 more
core +1 more source
Objective To explore the impact of artificial-intelligence perceptual learning when performing the ultrasound-guided popliteal sciatic block. Methods This simulation-based randomized study enrolled residents who underwent ultrasound-guided sciatic nerve ...
Nan Cai +9 more
doaj +1 more source

