Results 51 to 60 of about 30,589 (311)

Focal conduction block in the dorsal root ganglion in experimental allergic neuritis [PDF]

, 1992
Acute experimental allergic neuritis was induced in Lewis rats by inoculation with bovine intradural root myelin and adjuvants. In terminal experiments, sensory conduction was assessed in rats with hindlimb ataxia and weakness by stimulating the exposed ...
Blair, Cragg, Hahn, Hall, Heininger, Jacobs, Kadlubowski, Kraft, McCombe, McDonald, Pender, Pender, Pender, Pender, Pender, Rostami, Saida, Stanley, Strigård, Tuck, Tuck, Waksman, Waksman, Waksman, Wiethölter   +24 more
core   +1 more source

Electrically Evoked Compound Action Potentials in Spinal Cord Stimulation: Implications for Preclinical Research Models

Neuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Objectives The study aimed to assess the feasibility of recording electrically evoked compound action potentials (ECAPs) from the rat spinal cord. To achieve this, we characterized electrophysiological responses of dorsal column (DC) axons from electrical stimulation and quantified the relationship between ECAP and motor thresholds (ECAPTs and
Birte Elisabeth Dietz, Dave Mugan, Quoc Chi Vuong, Ilona Obara   +3 more
wiley   +1 more source

Effects of the addition of dexamethasone on postoperative analgesia after anterior cruciate ligament reconstruction surgery under quadruple nerve blocks

BMC Anesthesiology, 2021
Background Anterior cruciate ligament (ACL) reconstruction is an invasive surgical procedure for the knee. Quadruple nerve blocks including continuous femoral nerve block and single-injection sciatic, obturator, and lateral femoral cutaneous nerve blocks
Yuki Aoyama, Shinichi Sakura, Shoko Abe, Erika Uchimura, Yoji Saito   +4 more
doaj   +1 more source

Postoperative pain and morphine consumption after ultrasound-guided femoral and sciatic combined nerve block versus neurostimulation for femoral and sciatic combined nerve block or neurostimulation for femoral nerve block in primary elective total knee arthroplasty. [PDF]

, 2017
Congreso XXXVII National Meeting of the Spanish Society of Pharmacology with guest society: The British Pharmacological SocietyBackground and Aims: Total knee arthroplasty injuries are extremely painful and merit prompt attention to adequate ...
Bellido-Estevez, Inmaculada, Blanco-Reina, Encarnacion, Gomez-Luque, Jose Aurelio, Perez-Millón, V   +3 more
core  

The Role of Ionic Liquids at the Biological Interfaces in Bioelectronics

Advanced Science, EarlyView.
Ionic liquids (ILs) are highlighted as key artificial ionic materials that bridge biological ion‐based signaling and electronic devices. By understanding their composition, structure, function relationships, and mechanisms, ILs can advance from high performance electrolyte to core materials enabling integrated, multifunctional bioelectronics for ...
Yeong‐sinn Ye, Young Jin Jo, Ji Yeon Oh, Ju Yeon Jeong, Lili Guo, Tae‐il Kim   +5 more
wiley   +1 more source

Ultrasound Guided Continuous Sciatic Nerve Block for Acute Herpetic Neuralgia

Case Reports in Anesthesiology, 2019
Herpes Zoster (HZ) is the reactivation of a well-known viral disease which manifests itself with painful skin lesions. An effective analgesic method during the acute phase of HZ can contribute to decrease the incidence of postherpetic neuralgia (PHN) by ...
Thierry C. Bagaphou, Domenico Santonastaso, Eleonora Gargaglia, Lucia Norgiolini, Cinzia Tiburzi, Stefano Cristallini, Vittorio Cerotto, Fabio Gori   +7 more
doaj   +1 more source

Automated tracing of myelinated axons and detection of the nodes of Ranvier in serial images of peripheral nerves [PDF]

, 2015
The development of realistic neuroanatomical models of peripheral nerves for simulation purposes requires the reconstruction of the morphology of the myelinated fibres in the nerve, including their nodes of Ranvier.
Andres, Andriyenko, Auer, Berclaz, Breiman, Cardona, da Silva, Denk, Feria-Velasco, Frangi, Funke, Funke, Gierthmuehlen, Helmstaedter, Huelsenbeck, Hunter, Karnovsky, Kim, Kreshuk, Kuhn, Li, Li, Lindeberg, Liu, Lou, More, Novas, Nunez-Iglesias, Plachta, Plachta, Ramachandran, Romero, Sato, Schindelin, Schultze, Smith, Sommer, Vazquez-Reina, Vita, Yang, Zhang   +40 more
core   +1 more source

Deciphering and Targeting the Schwannoma‐Neuron‐Macrophage Crosstalk for the Treatment of Schwannomatosis and Associated Pain

Advanced Science, EarlyView.
We established patient‐derived SWN cell lines and orthotopic PDX models that recapitulate patient pain phenotypes, alongside a novel intravital DRG imaging platform to track macrophage infiltration and neuronal pain responses. Using these models, we define HMGB1–CCL2–IL‐6 signaling crosstalk driving pain and identify EGF signaling as a key regulator of
Zhenzhen Yin, Limeng Wu, Yanling Zhang, Yao Sun, Grace Y. Lee, Simeng Lu, Xing Gao, John W. Chen, Sonu Subudhi, William Ho, Chao Zhu, Jun Ren, Gino B. Ferraro, Alona Muzikansky, Anat Stemmer‐Rachamimov, Jianren Mao, Scott R. Plotkin, Lei Xu   +17 more
wiley   +1 more source

Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain

Advanced Science, EarlyView.
This work reveals that oligodendrocyte homeostasis, mediated by PDK1, is a critical determinant of neuropathic pain (NPP) pathogenesis. Disruption of PDK1 in oligodendrocytes impairs SOX10‐dependent myelination programs through c‐Myc accumulation, leading to disrupted myelination and the pathophysiology of NPP.
Pingping Qiao, Lifang Guo, Guochao Yang, Chaoli Huang, He Wang, Jian‐Jun Yang, Guiquan Chen, Yimin Hu   +7 more
wiley   +1 more source

Effects of early and late diabetic neuropathy on sciatic nerve block duration and neurotoxicity in Zucker diabetic fatty rats [PDF]

, 2017
Background The neuropathy of type II diabetes mellitus (DM) is increasing in prevalence worldwide. We aimed to test the hypothesis that in a rodent model of type II DM, neuropathy would lead to increased neurotoxicity and block duration after lidocaine ...
Blumenthal, S., Boeckh, R., de Girolami, U., Galley, H. F., Galley, H. F., Gerner, P., Hollmann, M. W., Lirk, P., Picardi, S., Stevens, M. F., ten Hoope, W., van Schaik, I. N., Verhamme, C.   +12 more
core