Ultrastructural analysis of sciatic nerves following nerve injury.
a-d, Representative images from semithin sciatic nerve cross sections taken from distal and proximal nerve parts, 5 weeks after crush injury. Genotypes as indicated. Arrows indicate degenerating myelin figures. Scale bar 20 μm.
Helen Morrison (781686) +7 more
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c-Jun reprograms Schwann cells of injured nerves to generate a repair cell essential for regeneration. [PDF]
The radical response of peripheral nerves to injury (Wallerian degeneration) is the cornerstone of nerve repair. We show that activation of the transcription factor c-Jun in Schwann cells is a global regulator of Wallerian degeneration.
Jenkins, Billy +33 more
core +1 more source
Untethered Electrical Stimulation Using Optoelectricity and Piezoelectricity for Tissue Regeneration
Untethered electrical stimulation from optoelectronic and piezoelectric materials can aid regeneration of damaged tissue. ABSTRACT Electrical signals are increasingly recognized as important regulators of tissue development and regeneration, with outcomes linked to behaviors including proliferation, differentiation, cell migration, and more.
Ryan Yao, Baochun Xu, Cunjiang Yu
wiley +1 more source
Hydrogel‐Based Bioelectronics: From Therapy and Sensing to Neuromorphic Computation
This review establishes a material–conduction–property–application framework connecting hydrogel chemistry and charge transport with therapy, sensing, closed‐loop feedback, and neuromorphic computation. ABSTRACT Bioelectronics establish bidirectional communication between living systems and electronic devices, providing an enabling platform for ...
Jianlong Hong +7 more
wiley +1 more source
Wearable acoustic bioelectronics for health monitoring and therapy
Wearable acoustic bioelectronics (WABEs) enable flexible, integrated, wireless, and miniaturized platforms for ultrasound‐based monitoring and therapeutic modulation. Abstract Wearable acoustic bioelectronics (WABEs) are an emerging class of body‐coupled acoustic systems that integrate ultrasound transducers with miniaturized electronics, spanning skin‐
Jinli Tang +10 more
wiley +1 more source
Sciatic neurotmesis and periostitis ossificans progressiva due to a traumatic/unexpected glass injury: a case report [PDF]
Peripheral nerves may be affected or injured for several reasons. Peripheral nerve damage can result from trauma, surgery, anatomical abnormalities, entrapment, systemic diseases, or iatrogenic injuries. Trauma and iatrogenic injuries are the most common
Berkay Yalçınkaya +3 more
doaj +1 more source
Neuroprotective effects of ozone therapy after sciatic nerve cut injury
A number of antioxidants have been used to treat peripheral nerve injury. However, there are few definitive experimental studies of ozone therapy for peripheral nerve cut injury.
Sarikçioǧlu, Levent +4 more
core +1 more source
Conformal fiber bioelectronics: Bridging flexible electronics and precision medicine
Conformal fiber bioelectronics for sensing, biomedical applications, and clinical devices toward precision medicine. Abstract Fiber‐based bioelectronic devices have emerged as a compelling platform for wearable and implantable health technologies, owing to their one‐dimensional topology, mechanical compliance, textile integrability, and compatibility ...
Yue Zhao +15 more
wiley +1 more source
ABSTRACT Oxaliplatin is a platinum‐based anticancer agent widely used for gastrointestinal malignancies; however, it is known to cause dose‐dependent peripheral neuropathy (OIPN), a characteristic adverse effect. OIPN results in a reduced quality of life and often necessitates dose reduction or discontinuation of oxaliplatin; however, effective ...
Yusuke Koura +11 more
wiley +1 more source
Slit1 and Robo2 protein are not expressed in the distal sciatic nerve stump after injury.
Western blot shows the disappearance of Slit1 and Robo2 protein in the distal nerve stump following a sciatic nerve transection injury. Slit1 and Robo2 protein are present in the intact sciatic nerve (Control) and also within the proximal nerve stump 4 ...
Lauren Carr (3779413) +2 more
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