Results 71 to 80 of about 1,587,270 (262)
Advanced Science, EarlyView.Administration of opioids activates ephrinB2‐EphB1 receptor signaling. Activated EphB1 receptors induce GRK2‐mediated phosphorylation of MOR at Ser375, which initiates the internalization of MOR and reduces opioid antinociception at the behavioral level. ABSTRACT Opioids are the primary treatment for severe pain in clinical practice.
Bo Peng +7 more
wiley +1 more source
Advanced Science, EarlyView.This review presents a pathology‐driven framework unifying nanomedicine across TBI, SCI, and PNI. Epidemiological evidence and comparative single‐cell transcriptomic reanalysis define shared pathological modules, injury‐specific effectors, and therapeutic bottlenecks. Six functional paradigms connect nanomaterial structure and biological fate to injury‐
Mouyuan Sun +12 more
wiley +1 more source
Molecular Pain, 2018 Objective Neural stem cells play an important role in the recovery and regeneration of peripheral nerve injury, and the microRNA-7 (miR-7) regulates differentiation of neural stem cells.
Nan Zhou +7 more
doaj +1 more source
An Active Knee–Ankle–Foot Orthosis With Torque‐Dense, Low‐Impedance Knee Actuation
Advanced Intelligent Systems, EarlyView.This article presents the simulation, design, and clinical validation of a robotic active KAFO with torque‐sensitive actuation. By passively and continuously adapting the transmission ratio in response to the knee torque, the torque‐sensitive actuator overcomes the tradeoff between torque, weight, and impedance observed in conventional robot actuators,
Brendon Ortolano +4 more
wiley +1 more source
Brain injury in combination with tacrolimus promotes the regeneration of injured peripheral nerves
Neural Regeneration Research, 2017 Both brain injury and tacrolimus have been reported to promote the regeneration of injured peripheral nerves. In this study, before transection of rat sciatic nerve, moderate brain contusion was (or was not) induced.
Xin-ze He +8 more
doaj +1 more source
Avaliação das repercussões do exercício físico sobre a regeneração nervosa de ratos Wistar submetidos a axonotmese do nervo isquiático [PDF]
, 2014 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação Multicêntrico em Ciências Fisiológicas, Florianópolis, 2014.Lesões do sistema nervoso periférico são comuns e acarretam perdas tanto
Guedert, Denis Guilherme
core
The mechanism of labor in nonhuman primates: A look inside
The Anatomical Record, EarlyView.Abstract While in humans, the flexed position of the fetus and its rotating course down the birth canal are well documented, in other primates the mechanism of labor is unknown. Despite the lack of comparative data, it is commonly assumed that the human obstetric mechanism is unique, and anthropologists have disputed when and why the transition to the ...
Melissa K. Stoller
wiley +1 more source
Changes in microtubule-associated protein tau during peripheral nerve injury and regeneration
Neural Regeneration Research, 2016 Tau, a primary component of microtubule-associated protein, promotes microtubule assembly and/or disassembly and maintains the stability of the microtubule structure. Although the importance of tau in neurodegenerative diseases has been well demonstrated,
Guang-bin Zha +3 more
doaj +1 more source
The Functional Results of Acute Nerve Grafting in Traumatic Sciatic Nerve Injuries
Turkish Journal of Trauma and Emergency Surgery, 2013 The sciatic and peroneal nerves are the most frequently injured in lower extremities, followed by tibial and femoral nerves. The aim of this study is to evaluate the functional results of acute nerve grafting in traumatic sciatic nerve injuries.A total of 9 patients with sciatic nerve defect were treated with primary nerve grafting. The mean age was 31.
Karaca, Can +4 more
openaire +4 more sources
Smaller Ischiofemoral Space Is Associated With Proximal Hamstring Injuries
Arthroscopy, Sports Medicine, and Rehabilitation, EarlyView.Purpose To develop a reference ischiofemoral space (IFS) value for patients with proximal hamstring injuries (HSI) and to compare it with individuals without proximal hamstring pathology. Methods We retrospectively collected the data from our institution. Patients aged 18 years or older with a proximal HSI were included.
Thun Itthipanichpong +4 more
wiley +1 more source