Results 171 to 180 of about 1,587,270 (262)

Comparison of the Effects of Botulinum Toxin Doses on Nerve Regeneration in Rats with Experimentally Induced Sciatic Nerve Injury. [PDF]

Toxins (Basel), 2023
Hwang S, Seo M, Lee TH, Lee HJ, Park JW, Kwon BS, Nam K.   +6 more
europepmc   +1 more source

ZBTB18 Dysfunction Promotes Neuropathic Pain via CHD4‐based Epigenetic Disinhibition of CLIC1 Channels in Sensory Neurons

Advanced Science, Volume 13, Issue 63, 12 November 2026.
In this study, we identify a novel functional role of ZBTB18 in regulating trigeminal‐mediated neuropathic pain. Nerve injury reduces ZBTB18 in trigeminal ganglion neurons, impairing CHD4/NuRD recruitment and de‐repressing Clic1. Elevated CLIC1 enhances chloride channel activity and neuronal hyperexcitability, thereby driving pain.
Shoupeng Wang, Zitong Huang, Yu Tao, Yunmei Zhang, Yufang Sun, Dongsheng Jiang, Weiwei Lu, Fuhai Ji, Gang Chen, Min Xu, Yuan Zhang, Jin Tao   +11 more
wiley   +1 more source

ROCK inhibition promotes axon and myelin regeneration via PI3K/Akt/GSK3β in a mouse sciatic nerve injury model. [PDF]

Int J Mol Med
Dou S, Li Z, Zheng B, Ren Z, Wang H, Zuo Q, Fang F, Zhuang Y.   +7 more
europepmc   +1 more source

Establishing Sensory Neurons as Therapeutic Targets in Peripheral Neuropathy Driven by Polyglutamine Expanded Murine ATXN3

Annals of Neurology, Volume 100, Issue 5, Page 1039-1054, November 2026.
Repeat expansion disorders frequently involve peripheral neuropathy, yet mechanisms remain unclear. Using a spinocerebellar ataxia type 3 (SCA3) Knock‐In Atxn3Q300/Q6, we identify progressive sensorimotor deficits, peripheral nerve pathology, and dorsal root ganglia RNA splicing dysregulation.
Juan P. Mato, John M. Hayes, Jacen Emerson, Maeha Sridharan, Toluwani Adelaja, Arsal Naeem, Alexandra F. Putka, Hayley S. McLoughlin   +7 more
wiley   +1 more source

In Vivo Study on 3D-Printed Polylactic Acid Nerve Tubes for Sciatic Nerve Injury Treatment. [PDF]

Polymers (Basel)
Kavuncu S, Hamid R, Sarıahmetoğlu ÖF.
europepmc   +1 more source

Methacrylated Gelatin and Graphene Oxide Hybrid Hydrogels Composed‐Bioinks for 3D Tissue Engineering

Advanced NanoBiomed Research, Volume 6, Issue 11, November 2026.
Bioinks made from hydrogels, such as methacrylated gelatin (GelMA), serve as the base material for bioprinted tissues, offering versatility and biocompatibility for a range of applications. Additional components however are still needed to improve functionality and mechanical stability of hydrogels. One of these components is graphene oxide (GO), added
Wanessa S. Mota, Erika S. Lisboa, Victoria L. S. dos Santos, Carine Serafim, Maria L. F. Bezerra, Thais F. R. Alves, Marco V. Chaud, Frederico S. Martins, Juliana C. Cardoso, Eliana B. Souto, Patrícia Severino   +10 more
wiley   +1 more source

Effectiveness of filling structures within nerve guidance conduits in a rat sciatic nerve injury model. [PDF]

Regen Ther
Kasuya T, Nishimoto S, Iwahashi T, Sayanagi J, Hirai Y, Shimada T, Yoshimura Y, Konishi K, Konishi M, Shiode R, Miyamura S, Oka K, Murase T, Okada S, Tanaka H.   +14 more
europepmc   +1 more source

Structural Allograft Reconstruction for Chronic Proximal Hamstring Avulsion Yields Significant Functional Improvement, Acceptable Satisfaction, but Limited Return to Preinjury Sport Levels

Arthroscopy, Volume 42, Issue 11, Page 2508-2516, November 2026.
Purpose To evaluate midterm outcomes of structural allograft reconstruction in patients with chronic proximal hamstring avulsion injuries. Methods This was a retrospective cohort study (minimum 2‐year follow‐up) including patients who underwent allograft surgical reconstruction for proximal hamstring avulsion injuries between 2016 and 2023. The primary
Nicolas Lefèvre, Mohamad K. Moussa, Eugénie Valentin, Yoann Bohu, Antoine Gerometta, Frederic Khiami, Alain Meyer, Olivier Grimaud, Alexandre Hardy   +8 more
wiley   +1 more source

Electroacupuncture alleviates sciatic nerve injury in sciatica rats by regulating BDNF and NGF levels, myelin sheath degradation, and autophagy. [PDF]

Open Life Sci
Liu Z, Zhang Q, Zhang X, He Q, Tian Y.
europepmc   +1 more source

Suspected Gluteal Epithelioid Sarcoma Complicated by Secondary Infection and Sciatic Neuropathy: A Case Report

Clinical Case Reports, Volume 14, Issue 11, November 2026.
ABSTRACT Secondary infection can coexist with and obscure an underlying soft‐tissue sarcoma. A deep mass that persists or progresses despite drainage and appropriate antibiotics, especially with progressive neurological deficit, warrants image‐guided core biopsy and sarcoma‐center referral before further surgery.
Baraa Nassar, Rawan Omar Nayfeh, Eman Sheikhasan, Saif Khaled Abdalhadi Azzam, Mohammedali Atef Abumayyala   +4 more
wiley   +1 more source