Results 151 to 160 of about 1,587,270 (262)

Integrated Phytochemical Characterisation, Pharmacological Evaluation and Computational Investigation of Acampe papillosa Stem Extract

Analytical Science Advances, Volume 7, Issue 2, December 2026.
The pharmacological potential of the methanolic stem extract of Acampe papillosa is evaluated using in vivo and in silico approaches. The extract demonstrates significant anxiolytic, sedative, anti‐inflammatory, and antipyretic activities in experimental models, while molecular docking supports the observed biological effects through favorable ...
Qurratul Ain Sadia, Sadia Tamanna Tamim, Faruq Mohammed Tashriq, Nasir Uddin, Fatematus Zhohara Alam Hima, Ulfat Sobha Surat, Mily Khastagir, Muhammad Abdul Jalil, Md. Hossain Rasel, Arman Ullah Rafi, S. M. Moazzem Hossen   +10 more
wiley   +1 more source

Iatrogenic Sciatic Nerve Injury Following Surgical Treatment of an Acetabular Fracture: A Case Report of Conservative Management. [PDF]

Cureus
Aoussaf A, Elhamlili S, Elmir S.
europepmc   +1 more source

Schwann Cell‐Specific ATG7‐Dependent Autophagy Protects Myelin in a Mouse Model of Krabbe Disease

Glia, Volume 74, Issue 12, December 2026.
Krabbe disease (KD) is caused by mutations in GALC and deregulated lysosomal function in Schwann cells (SCs). Using a SC‐specific Galc‐cKO mouse, we identified altered autophagy in SCs during KD progression. Further ablation of Atg7 in SCs of KD worsened disease severity.
Narayan Dhimal, Aditya Sidharth, Jiajun Zhang, Trina Rudra, Edward Hurley, Pablo M. Paez, Fraser J. Sim, Daesung Shin, M. Laura Feltri   +8 more
wiley   +1 more source

Evaluating the Neuroprotective Effects of Levetiracetam on Experimental Sciatic Nerve Injury. [PDF]

J Clin Med
Demiriz Gulmez D, Hacioglu G, Cinar E, Keskin A, Cuvas Apan O, Apan A.   +5 more
europepmc   +1 more source

Disruption of Lactate Metabolism in the Peripheral Nervous System Leads to Motor‐Selective Deficits

Glia, Volume 74, Issue 12, December 2026.
To test the importance of lactate metabolism and shuttling between Schwann cells and neurons in the PNS, we selectively knocked out both LDHA and LDHB in motor neurons, sensory neurons, or Schwann cells. ABSTRACT Schwann cells (SCs) myelinate and provide trophic support to axons in the peripheral nervous system (PNS).
A. Joseph Bloom, Shweta Tendulkar, Amber R. Hackett, Amy Strickland, Yurie Sato‐Yamada, Liya Yuan, Wendy Dong, Joseph Ippolito, Robert E. Schmidt, Yo Sasaki, Aaron DiAntonio, Jeffrey Milbrandt   +11 more
wiley   +1 more source

Mitochondrial Transplantation Preserves Regenerative Capacity of Denervated Skeletal Muscle by Disrupting a Ca2+ Overload‐Mitophagy‐Ferroptosis Circuit

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 6, December 2026.
ABSTRACT Background Denervation‐induced muscle atrophy progresses during the interval between nerve injury and reinnervation, and depletion of muscle satellite cells (MuSCs) contributes to impaired functional recovery. Although mitochondrial dysfunction and impaired quality control are implicated in muscle wasting, whether excessive mitochondrial ...
Haiqi Ding, Jiagu Huang, Jiayao Zhang, Zhizhen He, Jun Luo, Zhao Lin, Linhai Yang, Yibin Su, Mingjuan Zhang, Fuli Wen, Yuan Lin, Cheng Chang, Hanhao Dai, Xuehui Ge, Jie Xu   +14 more
wiley   +1 more source

Hypoxia-induced Schwann cells-derived extracellular vesicles carrying LncRNA TNXA-PS1 promote recovery post sciatic nerve injury. [PDF]

Commun Biol
Hao Z, Wang Z, Jia J, Wang Y, Wu T, Fan Y, Huo Z, Zhao X, Yan S, Wang B, Qicheng A.   +10 more
europepmc   +1 more source

ZIF‐8‐Based Nanodelivery of Tectorigenin for Alleviating Skeletal Muscle Atrophy via Inhibition of Oxidative Stress and Inflammation

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 6, December 2026.
ABSTRACT Background Skeletal muscle atrophy is a pathological condition characterized by a progressive loss of muscle mass and function. Its core mechanisms involve an imbalance between protein synthesis and degradation, caused by oxidative stress and inflammation.
Xia Li, Yutong Wei, Lei Qi, Xiu Dai, Zhanzhan Li, Chuli Zhu, Xucheng Zhu, Yuntian Shen, Bingqian Chen, Xiaosong Gu, Hualin Sun, Xinlei Yao   +11 more
wiley   +1 more source

Evaluation of Dexamethasone and Swimming Exercise as Complementary Interventions in a Rat Sciatic Nerve Injury Model. [PDF]

Antioxidants (Basel)
Karakoç M, Ayaz H, Çelik F, Aşır F.
europepmc   +1 more source

Recovery From Persistent Phrenic Nerve Palsy Following Pulsed Field Ablation: A Case Report

Journal of Arrhythmia, Volume 42, Issue 6, December 2026.
Persistent phrenic nerve palsy is a rare but possible complication of pulsed field ablation. We report recovery of phrenic nerve function approximately 6 months after PulseSelect ablation and discuss potential mechanisms and preventive strategies, including the effects of repeated applications and their spatial distribution around the right superior ...
Tatsuya Hayashi, Shingo Yamamoto, Jumpei Ohashi, Midori Sato, Eiichi Shiraki, Yuya Watanabe, Yoshiki Asano, Kenichi Sakakura, Hideo Fujita   +8 more
wiley   +1 more source