Results 31 to 40 of about 220,539 (258)
Tadalafil Promotes the Recovery of Peripheral Neuropathy in Type II Diabetic Mice. [PDF]
PLoS ONE, 2016 We previously demonstrated that treatment of diabetic peripheral neuropathy with the short (4 hours) half-life phosphodiesterase 5 (PDE5) inhibitor, sildenafil, improved functional outcome in diabetic db/db mice.
Lei Wang +7 more
doaj +1 more source
Sciatic neuropathy with preserved sensory nerve action potentials, a case series [PDF]
, 2020 Background: Sciatic neuropathy is differentiated from lumbosacral radiculopathy based on the finding of abnormal sensory nerve action potentials (SNAPs). Cases of sciatic neuropathy with intact SNAPS have not been well described. Methods: A retrospective
Li, Yuebing +2 more
core +2 more sources
Sciatic nerve microvascular permeability in type 2 diabetes decreased in patients with neuropathy
Annals of Clinical and Translational Neurology, 2022 Clinical and histological studies have found evidence that nerve ischemia is a major contributor to diabetic neuropathy (DN) in type 2 diabetes (T2D).
Johann M E Jende +9 more
semanticscholar +1 more source
Molsidomine ameliorates diabetic peripheral neuropathy complications in Wistar rats
Animal Models and Experimental Medicine, 2021 Diabetic neuropathy is a disorder that affects various regions of the nervous system and there is no specific treatment available for it. This study evaluated the protective effect of molsidomine in diabetic neuropathy in rats.
Pranav Nayak B +2 more
doaj +1 more source
Pediatric sciatic neuropathy: Clinical presentation and long term follow up.
Revista chilena de pediatría, 2020 INTRODUCTION Sciatic neuropathy is rare and difficult to diagnose in pediatrics, and its long-term course has not been completely understood. OBJECTIVE To analyze the clinical presentation and evolution of a group of pediatric patients with sciatic ...
Carlos Jaque-Almendras +8 more
semanticscholar +1 more source
Stem Cells International, 2021 Painful neuropathy is a common adverse effect of oxaliplatin (OXL), a platinum-derivative chemotherapeutic agent. Oxidative stress and mitochondrial dysfunction are key factors contributing to the development of OXL-induced peripheral neuropathy (OIPN ...
Anna Lethicia L. Oliveira +7 more
doaj +1 more source
Neural Regeneration Research, 2023 Circular RNAs (circRNAs) play a vital role in diabetic peripheral neuropathy. However, their expression and function in Schwann cells in individuals with diabetic peripheral neuropathy remain poorly understood.
Yu-Tian Liu +12 more
doaj +1 more source
Lipin1 Alleviates Autophagy Disorder in Sciatic Nerve and Improves Diabetic Peripheral Neuropathy
Molecular Neurobiology, 2021 Diabetic peripheral neuropathy (DPN) is a chronic complication of diabetes, and its neural mechanisms underlying the pathogenesis remain unclear. Autophagy plays an important role in neurodegenerative diseases and nerve tissue injury.
Meijian Wang +9 more
semanticscholar +1 more source
Acute- and late-phase matrix metalloproteinase (MMP)-9 activity is comparable in female and male rats after peripheral nerve injury. [PDF]
, 2018 BACKGROUND:In the peripheral nerve, pro-inflammatory matrix metalloproteinase (MMP)-9 performs essential functions in the acute response to injury. Whether MMP-9 activity contributes to late-phase injury or whether MMP-9 expression or activity after ...
Angert, Mila +6 more
core +2 more sources
Frontiers in Immunology, 2022 Leukocyte infiltration and persistence within peripheral nerves have been implicated in chronic nociception pathogenesis in murine peripheral neuropathy models.
Chaoling Dong, Eroboghene E. Ubogu
doaj +1 more source