Results 51 to 60 of about 23,100 (268)

Inhibition of neurite outgrowth in differentiating mouse N2a neuroblastoma cells by phenyl saligenin phosphate: Effects on MAP kinase (ERK 1/2) activation, neurofilament heavy chain phosphorylation and neuropathy target esterase activity [PDF]

, 2006
Sub-lethal concentrations of the organophosphate phenyl saligenin phosphate (PSP) inhibited the outgrowth of axon-like processes in differentiating mouse N2a neuroblastoma cells (IC50 2.5 μM).
Abou-Donia, Abou-Donia, Alan J. Hargreaves, Barber, Barber, Brunet, Casida, Chambers, Denizot, Ehrich, El-Fawal, Eto, Flaskos, Flaskos, Forshaw, Fowler, Glynn, Glynn, Gupta, Hatch, Henschler, Ian C. Coutts, James, Jensen, John Flaskos, Johnson, Johnson, Johnson, Jortner, Jortner, Keilbaugh, Laemmli, Lee, Li, Lowry, Magdalini Sachana, Mary Bountouri, Maxine J. Fowler, Nixon, Nomeir, Nomeir, Nostrandt, Nostrandt, Paul Glynn, Perron, Rosenstock, Schmuck, Sharma, Song, Suwita, Towbin, Van Teinhoven, Veeranna, Veronesi, W. Graham McLean, Wayne Harris, Zhao   +56 more
core   +1 more source

Ionic–Bionic Interfaces: Advancing Iontronic Strategies for Bioelectronic Sensing and Therapy

Advanced Science, EarlyView.
Ionic–bionic interfaces for bioelectronics leverage ions as multifunctional mediators that combine mechanical compliance, ionic and electronic functionalities, and therapeutic effects. These systems offer real‐time biosignal transduction, effective wound dressing, responsive drug delivery, and seamless interaction between soft tissues and electronic ...
Yun Goo Ro, Yoojin Chang, Jeeyoon Kim, Seungjae Lee, Sangyun Na, Cheolhong Park, Hyunhyub Ko   +6 more
wiley   +1 more source

The alternatively spliced fibronectin CS1 isoform regulates IL-17A levels and mechanical allodynia after peripheral nerve injury. [PDF]

, 2015
BackgroundMechanical pain hypersensitivity associated with physical trauma to peripheral nerve depends on T-helper (Th) cells expressing the algesic cytokine, interleukin (IL)-17A.
Angert, Mila, Chernov, Andrei V, Dolkas, Jennifer, Hoang, Khan, Liu, Huaqing, Nishihara, Tasuku, Remacle, Albert G, Shiryaev, Sergey A, Shubayev, Veronica I, Strongin, Alex Y   +9 more
core   +3 more sources

Neuropathic Pain and Enlarged Nerves in Adult Noonan Syndrome and Noonan Syndrome With Multiple Lentigines: Health‐Related Quality of Life and Neurologic Symptoms

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Noonan syndrome (NS) and the clinically related Noonan syndrome with multiple lentigines (NSML) belong to the group of RASopathies. Although pain is not mentioned as a characteristic feature, it has recently been reported as a clinically significant problem.
Jos M. T. Draaisma, Wesley Reintjes, Erika Leenders, Fieke Draaisma, Melanie Burgers, Lotte Kleimeier, Marco Tartaglia, Merel Klaassens, Ruud Becks, Steven Renes, Ellen Wingbermühle, Nicol C. Voermans, Nens van Alfen   +12 more
wiley   +1 more source

N-acetyl-L-cysteine mitigates diabetes-induced impairments in sciatic nerve

IBRO Neuroscience Reports
Diabetic neuropathy is a consequence of long-term hyperglycemia. The emergence of neuronal condition is a result of hyperglycemia-induced oxidative stress.
Sukhdev S. Kamboj, Satya P. Sharma, Wael M.Y. Mohamed, Rajat Sandhir   +3 more
doaj   +1 more source

Postpartum sciatic neuropathy [PDF]

Neurology, 2016
A 32-year-old woman presented with a left foot drop for 2 weeks after Caesarean section following an 11-hour labor. Nerve conduction studies (NCS) and EMG revealed sciatic neuropathy.1 Pelvic T2-weighted imaging demonstrated diffuse high signal intensity and swelling of the sciatic nerve.
Yeonji, Yoo, Sung Jun, Kim, Jeehae, Oh
openaire   +2 more sources

Dysregulation of NAD+ metabolism induces a Schwann cell dedifferentiation program [PDF]

, 2018
The Schwann cell (SC) is the major component of the peripheral nervous system (PNS) that provides metabolic and functional support for peripheral axons. The emerging roles of SC mitochondrial function for PNS development and axonal stability indicate the
Hackett, Amber R, Kim, Sungsu, Milbrandt, Jeffrey, Sasaki, Yo, Strickland, Amy   +4 more
core   +1 more source

Vasa Nervorum in rat major pelvic ganglion are innervated by nitrergic nerve fibers [PDF]

, 2013
INTRODUCTION The vasa nervorum comprises a network of small diameter blood vessels that provide blood supply to nerves and ganglia. The cell bodies of autonomic nerves innervating the urogenital organs are housed in the major pelvic ganglia (MPG) in rats.
Ames, Andersson, Appenzeller, Asif Muneer, Benesova, Benesova, Cameron, Cameron, Cameron, Cellek, Cellek, Cellek, Cellek, Chandrasekharan, Chantrain, Chung, Dail, Dashwood, Dixon, Giuliano, Gonzalez‐Hernandez, Hackett, Hlaing, Iadecola, Kalsi, Karl A. Beetson, Kavdia, Kedia, Kobayashi, Low, Mary A. Cotter, Mbaku, McManis, Melikian, Norman E. Cameron, Padma‐Nathan, Porst, Saenz de Tejada, Schirar, Selim Cellek, Sonntag, Stephanie F. Smith, Stuehr, Tabatai, Toda, Toda, Toda, Toque, Vitullo, Wang   +49 more
core   +1 more source

Metabolic and biochemical profiling reveals phenotypic heterogeneity in Zucker diabetic fatty rats

Animal Models and Experimental Medicine, EarlyView.
Genetically uniform Zucker Diabetic Fatty (ZDF) rats spontaneously develop four distinct metabolic phenotypes despite identical housing and diet conditions. Each phenotype exhibits unique biomarker signatures encompassing glucose homeostasis, insulin secretion, polyol pathway activation, oxidative stress, inflammatory cytokines, and neurotrophic ...
Marek Lepáček, Pavol Boďo, Barbora Kaločayová, Marta Šoltésová Prnová   +3 more
wiley   +1 more source

Sildenafil ameliorates long term peripheral neuropathy in type II diabetic mice. [PDF]

PLoS ONE, 2015
Diabetic peripheral neuropathy is a common complication of long-standing diabetes mellitus. To mimic clinical trials in which patients with diabetes enrolled have advanced peripheral neuropathy, we investigated the effect of sildenafil, a specific ...
Lei Wang, Michael Chopp, Alexandra Szalad, LongFei Jia, XueRong Lu, Mei Lu, Li Zhang, Yi Zhang, RuiLan Zhang, Zheng Gang Zhang   +9 more
doaj   +1 more source