Results 121 to 130 of about 47,052 (316)

Mechanisms of spinal glial activation in chemotherapy‐induced peripheral neuropathy: Focus on microglia and astrocytes

open access: yesIbrain, EarlyView.
Chemotherapy‐induced peripheral neuropathy (CIPN) remains a major clinical challenge, with central sensitization considered an important pathological mechanism in its occurrence and persistence. This review focuses on spinal astrocytes and microglia, systematically summarizing the pathological mechanisms of spinal glial cells involved in CIPN caused by
Long Gu, Song Cao, Yonghuai Feng
wiley   +1 more source

Traction for low back pain, the evidence is flawed : a thesis presented in partial fulfilment of the requirements for the Masters of Health Science (MHlthSci) in Environmental Health at Massey University Campus, Wellington, New Zealand [PDF]

open access: yes, 2017
Research suggests the burden of low back pain is growing despite recent advances in investigative technology and the explosion in research. Evidence based practice is necessary within physiotherapy. However, the best evidence component must be clinically
Plumbley, Grant David
core  

Molecular imprinting for neurology: Materials, applications, and limitations

open access: yesIbrain, EarlyView.
Molecularly imprinted materials: diagnostic, therapeutic and research applications in neurology. Molecularly imprinted materials offer high specificity and affinity for target molecules in neurological applications. This review highlights their synthesis, characterisation, and use in diagnostics, research and therapeutics.
Xiaohan Ma   +3 more
wiley   +1 more source

A Case of a Durable Partial Response to Late‐Line Axitinib Following Prior Use of Tyrosine Kinase Inhibitors in Metastatic Papillary Renal Cell Carcinoma

open access: yesIJU Case Reports, EarlyView.
ABSTRACT Introduction Metastatic papillary renal cell carcinoma (PRCC) is associated with a poor prognosis. Many patients with PRCC respond to first‐ and second‐line systemic chemotherapy treatments; however, few respond to late‐sequence treatment.
Naoto Hodotsuka   +7 more
wiley   +1 more source

When is discectomy indicated for lumbar disc disease? [PDF]

open access: yes, 2011
Emergent discectomy is indicated in the presence of cauda equina and severe, progressive neuromotor deficits (strength of recommendation [SOR]: C, expert opinion).
Brown, Rhett   +3 more
core  

Prevalence and Mechanisms of Sustained Force Production in the Musculature of the Southern Alligator Lizard (Elgaria multicarinata)

open access: yesJournal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
ABSTRACT The southern alligator lizard (Elgaria multicarinata) exhibits prolonged mate‐holding behavior. This behavior maybe be underpinned by a phenomenon known as sustained force, observed in the jaw muscles of this species, in which the muscle fails to relax between subsequent contractions.
Allyn Nguyen   +3 more
wiley   +1 more source

Improving Patient Decision-Making in Health Care [PDF]

open access: yes, 2011
Outlines regional variations within Minnesota in rates of patients with similar conditions receiving elective surgery, the concept of shared decision making, treatment choices for eight conditions, and steps for ensuring patients make informed ...
David C. Goodman   +5 more
core  

Spinal endoscopy for chronic sciatica [PDF]

open access: bronze, 2005
John Richardson   +2 more
openalex   +1 more source

Sciatic Nerve Stimulation Mitigates Depression‐Like Behaviors and Memory Deficits in Stressed Mice

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Stress causes depression and cognitive decline. With limitations in pharmacotherapy, sciatic nerve stimulation (SNS) offers a promising nondrug alternative. This study aimed to explore the therapeutic efficacy of SNS in mitigating stress‐induced depressive behaviors and memory deficits by focusing on astrocytic dysfunction and cellular ...
Chih‐Hao Tien   +10 more
wiley   +1 more source

Lysosome Evanescence Mediates Autophagic Flux Impairment in Glucose Imbalanced Environments

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Schwann cells (SCs) support axonal function and promote nerve regeneration. This study investigated how various glucose concentrations influence SC viability, oxidative stress, and autophagy, which contribute to diabetic neuropathy. RSC96 SCs were cultured under five glucose conditions (0, 2.5, 5.5, 50, or 100 mM) for 24, 48, and 72 h.
Yuan‐Chen Cheng   +6 more
wiley   +1 more source

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