The effects of ZnO, fullerene C60 and polyaniline (PANI) nanoparticles in hybrid nerve conduits are explored. The composites show enhanced electrical conductivity, permeability to physiological fluids and mechanical stability. The biocompatibility of composites is confirmed by in vivo and in vitro studies.
Liudmyla Sukhodub +7 more
wiley +1 more source
Causal effect of education on low back pain, intervertebral disc degeneration and sciatica: Mendelian randomization study. [PDF]
Wu Z +7 more
europepmc +1 more source
Lymphatic topology reveals a novel intranodal lympho‐venous shunt
Abstract Understanding the lymphatic network is crucial for immunological research. Currently, a complete map of lymphatic drainage in mice is lacking. We present a detailed lymphatic system flow dynamic of two mouse strains with swollen lymph nodes (LNs), using region‐specific tracer injection and high‐resolution micro‐CT imaging to characterize LN ...
Ariunbuyan Sukhbaatar +5 more
wiley +1 more source
Saudi Clinical Practice Guideline for the Assessment and Management of Low Back Pain and Sciatica in Adults. [PDF]
Aldera M +16 more
europepmc +1 more source
Effects of Tibial Nerve Electrostimulation in Patients With Fecal Incontinence: A Systematic Review
ABSTRACT Background and Objective Fecal incontinence (FI) is a condition characterized by the involuntary loss of stool, resulting from the inability to control the sphincter and neuromuscular mechanisms responsible for continence. Percutaneous electrical stimulation of the posterior tibial nerve (posterior tibial nerve stimulation—PTNS) has been used ...
Janaina dos Santos Sóstennes +6 more
wiley +1 more source
Sciatic Schwannoma in a Patient with Neurofibromatosis Type 1: A Report of a Minimally Invasive Surgical Technique and Review of the Literature. [PDF]
Sarpong EO +4 more
europepmc +1 more source
Testing of Pre‐Operative Peripheral Nerve Blocks in Randomised Controlled Trials: A Scoping Review
ABSTRACT Background Peripheral nerve blocks are widely used for anaesthesia in upper and lower limb surgery, but the methods used to assess their success vary substantially. This scoping review examined contemporary research practises and the extent to which trials report on peripheral nerve block evaluation.
Aurelien‐Xuan Rosendal Bahuet +10 more
wiley +1 more source
Unraveling proteomic signatures and neuroinflammatory networks in a CCI rat model of early sciatica: insights for neuropathic pain mechanisms. [PDF]
Li X +7 more
europepmc +1 more source
Abstract Chronic pain, marked by nociceptive sensitization and maladaptive neuroplasticity, affects 30% of the global population with escalating socioeconomic burdens. Epidemiological data show a 2‐3‐fold increase in neuropsychiatric co‐morbidities among individuals with chronic pain, where epigenetic dysregulation serves as a key mechanism linking ...
Kai Zhang +18 more
wiley +1 more source
Druggable Genome-Wide Mendelian Randomization Identifies Distinct Therapeutic Targets for Low Back Pain, Intervertebral Disk Degeneration, and Sciatica. [PDF]
Sun A, Li Z, Du Y, Liu H, Zhan Q, Liu Z.
europepmc +1 more source

