Results 121 to 130 of about 46,496 (324)

When is discectomy indicated for lumbar disc disease? [PDF]

open access: yes, 2011
Emergent discectomy is indicated in the presence of cauda equina and severe, progressive neuromotor deficits (strength of recommendation [SOR]: C, expert opinion).
Brown, Rhett   +3 more
core  

Sciatic Nerve Stimulation Mitigates Depression‐Like Behaviors and Memory Deficits in Stressed Mice

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Stress causes depression and cognitive decline. With limitations in pharmacotherapy, sciatic nerve stimulation (SNS) offers a promising nondrug alternative. This study aimed to explore the therapeutic efficacy of SNS in mitigating stress‐induced depressive behaviors and memory deficits by focusing on astrocytic dysfunction and cellular ...
Chih‐Hao Tien   +10 more
wiley   +1 more source

Causal association between circulating inflammatory markers and sciatica development: a Mendelian randomization study

open access: yesFrontiers in Neurology
BackgroundThis research explores the causal association between circulating inflammatory markers and the development of sciatica, a common and debilitating condition.
Yang Wu   +4 more
doaj   +1 more source

Sciatica due to extrapelvic heterotopic ossification: A case report

open access: yesJournal of Medical Case Reports, 2008
Introduction Sciatica is a common problem, usually caused by disc herniation or spinal stenosis. Low back pain is also present in most cases. When sciatica is the unique clinical finding, especially in young patients, extraspinal pathology should be ...
Panagiotopoulos Elias C   +4 more
doaj   +1 more source

Cases of Sciatica [PDF]

open access: yesThe New England Journal of Medicine, Surgery and Collateral Branches of Science
n ...
Warren, J. C., Dearborn, H. A. S.
openaire   +2 more sources

Accelerated rehabilitation after proximal hamstring avulsion repair is safe and effective: Outcomes from randomized controlled trial of two different rehabilitation regimes

open access: yesKnee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose The purpose of the study was to identify the safety and effectiveness of an accelerated (AR) versus conservative (CR) rehabilitation regimen following surgical repair of proximal hamstring tendon avulsions. Methods This prospective randomized controlled trial (RCT) allocated patients undergoing proximal hamstring tendon repair to ...
Randeep S. Aujla   +7 more
wiley   +1 more source

Mesenchymal Stem Cell‐Engrafted Bacterial Cellulose and Graphene Oxide Scaffolds Enhance Peripheral Nerve Repair in a Rat Model

open access: yesMacromolecular Materials and Engineering, EarlyView.
This study investigates the use of graphene oxide‐decorated bacterial cellulose (BC/GO) scaffolds combined with mesenchymal stem cells (MSCs) to enhance axonal regeneration after sciatic nerve injury in rats. Graphene oxide is embedded monodispersely into the BC fibrillar matrix.
Ismail Simsek   +5 more
wiley   +1 more source

The Second Hit Hypothesis in Animal and Human Dystonia: The Role of Peripheral Nerve Trauma and Spinal Cord Injury

open access: yesMovement Disorders, EarlyView.
The “second‐hit” hypothesis proposes that both a genetic predisposition and an environmental insult—such as peripheral nerve trauma or spinal cord injury—are required for dystonia development. This review explores how neuroinflammation and maladaptive plasticity, triggered by nerve and spinal cord injury, contribute to dystonia pathogenesis.
Lisa Harder‐Rauschenberger   +1 more
wiley   +1 more source

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