Results 241 to 250 of about 47,052 (316)

Motion‐Style Scalp Acupuncture Ameliorates Post‐Stroke Muscle Spasticity Through Cerebral Blood Flow Augmentation and 5‐HT2AR‐Mediated Spinal KCC2 Reactivation

open access: yesBrain and Behavior, Volume 15, Issue 12, December 2025.
Pathology of PSS and the antispastic mechanism of MSSA: A focus on cerebral blood flow augmentation and 5‐HT2AR‐mediated KCC2 activation. Abbreviations: CST, corticospinal tract; CRT, corticoreticular tract, RST, reticulospinal tract; rCBF, regional cerebral blood flow; PSS, post‐stroke spasticity. ABSTRACT Background Muscle spasticity, a prevalent and
Qin‐Yong Zhang   +8 more
wiley   +1 more source

Bayesian-weighted Mendelian randomization reveals sleep apnea syndrome mediates the BMI-chronic pain link. [PDF]

open access: yesJ Thorac Dis
Shi W   +8 more
europepmc   +1 more source

Effect of Dezocine and Dexmedetomidine as Adjuvants in Ropivacaine for Incision Subcutaneous Infiltration Anesthesia on Incision Healing in Diabetic Rats

open access: yesBrain and Behavior, Volume 15, Issue 12, December 2025.
The adjunctive use of dezocine and dexmedetomidine with ropivacaine in incisional subcutaneous infiltration anesthesia may contribute to improved incision healing in diabetic rats. ABSTRACT Introduction Surgery can induce insulin resistance (IR) in diabetic patients, and severe IR compromises the body's ability to combat infection and shock, impairs ...
Lang Yu   +7 more
wiley   +1 more source

Primary Limb Leiomyosarcoma With Multifocal Musculoskeletal Soft Tissue Metastasis: A Case Report and Literature Review

open access: yesClinical Case Reports, Volume 13, Issue 12, December 2025.
Overview of a rare case of primary limb leiomyosarcoma presenting with multifocal musculoskeletal soft tissue metastases. ABSTRACT Leiomyosarcoma (LMS) is an aggressive soft‐tissue sarcoma that may rarely arise in the extremities and metastasize to multiple organs.
Milad Haji Agha Bozorgi   +2 more
wiley   +1 more source

Fibrolipomatous hamartoma of the sciatic nerve: an atypical case report. [PDF]

open access: yesFront Radiol
Al Ghamdi YH   +3 more
europepmc   +1 more source

Transient Receptor Potential Channels as Key Regulators of Neuroinflammation in Neurological Disorders: Mechanistic Insights, Therapeutic Potentials, and Future Directions

open access: yesCNS Neuroscience &Therapeutics, Volume 31, Issue 12, December 2025.
This study elucidates the central role of transient receptor potential (TRP) channels in driving neuroinflammation across neurological disorders. Acting as critical molecular sensors on neurons and glial cells, TRP channels' activation initiates downstream pathways that promote the release of proinflammatory cytokines, a pathological mechanism in ...
Daji Guo   +8 more
wiley   +1 more source

Impaired WNT3/IGF‐1 Signaling in Dorsal Dentate Gyrus Contributes to Chronic Pain‐Related Cognitive Impairment

open access: yesCNS Neuroscience &Therapeutics, Volume 31, Issue 12, December 2025.
Schematic diagram depicting the mechanism of SNI‐induced comorbidity of pain and cognition decline. SNI increased TNFα release in the dorsal DG (1); TNFα trigger a “double hit” to dorsal DG homeostasis: On the one hand, TNFα induced IGF‐1 resistance in granule neuron.
Yajie An   +8 more
wiley   +1 more source

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