Results 71 to 80 of about 24,008 (242)

The Clinical Efficacy of High‐Voltage Long‐Duration Pulsed Radiofrequency Treatment in Pudendal Neuralgia: A Retrospective Study

Neuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Background Patients with pudendal neuralgia (PN) experience long‐lasting chronic pain, hyperalgesia, and comorbid emotional disorders, such as depression and anxiety. Treatment via conventional pulsed radiofrequency (PRF) current carries a significantly high rate of failure.
Cheng‐Long Wang, Tao Song
wiley   +1 more source

3D Hydrogel Cell Cultures and Their Biomedical Applications

Advanced NanoBiomed Research, EarlyView.
The review highlights the advantages of hydrogel‐based 3D cell cultures over traditional 2D models. These hydrogels closely mimic natural cellular environments, improving research in tissue engineering, drug discovery, cancer studies, and neuroscience.
Tri Lan Thai, Arushi Manchanda, Sarah L. Higginbottom, Estrella Sanz Rodriguez, Richard Wilson, Eva Tomaskovic‐Crook, Jeremy M. Crook, Brett Paull   +7 more
wiley   +1 more source

Electrically Evoked Compound Action Potentials in Spinal Cord Stimulation: Implications for Preclinical Research Models

Neuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Objectives The study aimed to assess the feasibility of recording electrically evoked compound action potentials (ECAPs) from the rat spinal cord. To achieve this, we characterized electrophysiological responses of dorsal column (DC) axons from electrical stimulation and quantified the relationship between ECAP and motor thresholds (ECAPTs and
Birte Elisabeth Dietz, Dave Mugan, Quoc Chi Vuong, Ilona Obara   +3 more
wiley   +1 more source

New partial skeleton of Homo habilis from the upper Burgi Member, Koobi Fora Formation, Ileret, Kenya

The Anatomical Record, EarlyView.
Abstract KNM‐ER 64061 is a partial skeleton from the upper Burgi Member of the Koobi Fora Formation (2.02–2.06 Ma) associated taphonomically and geochemically with a nearly complete mandibular dentition (KNM‐ER 64060) attributed to Homo habilis.
Frederick E. Grine, Deming Yang, Ashley S. Hammond, William L. Jungers, Michael R. Lague, Carrie S. Mongle, Osbjorn M. Pearson, Meave G. Leakey, Louise N. Leakey   +8 more
wiley   +1 more source

Causal effects of skin microbiota on intervertebral disk degeneration, low back pain and sciatica: a two-sample Mendelian randomization study

Journal of Orthopaedic Surgery and Research
Objective The purpose of this study is to use two-sample Mendelian randomization (MR) to investigate the causal relationship between skin microbiota, especially Propionibacterium acnes, and intervertebral disc degeneration (IVDD), low back pain (LBP) and
Yuchao Jia, Houcong Chen, Shengbo Huang, Zhenxin Huo, Baoshan Xu   +4 more
doaj   +1 more source

Fiber‐type soft bioelectronics for wearable and implantable sensing and therapy

BMEMat, EarlyView.
Fiber‐type soft bioelectronics are emerging as versatile platforms for wearable and implantable health monitoring and therapeutic applications. These bioelectronics use organic and inorganic matrices combined with advanced fillers, which feature high conductivity, electrochemical sensitivity, softness, and biocompatibility.
Haneul Kim, Hak Yong Kim, Ja Hoon Koo, Gi Doo Cha, Dae‐Hyeong Kim, Hye Jin Kim   +5 more
wiley   +1 more source

Force stimulation promotes nerve regeneration by restoring cellular energy

BMEMat, EarlyView.
Mechanical stimulation can help nerves regenerate in various ways. We developed two devices (a piezo‐motor‐driven stretching device and a SAW‐based actuator) to apply mechanical stimulation to sciatic nerve and DRG neurons. Our study shows that appropriate mechanical force stimulation can promote regeneration by restoring the energy supply to the ...
Zhe Wang, Chen Cai, Hetao Xie, Yupeng Yang, Lei Li, Nik Ahmad Nizam Nik Malek, Wan Hairul Anuar Kamaruddin, Meiwan Chen, Yuanhua Sang, Bing Ji, Zenan Wang   +10 more
wiley   +1 more source

Advances in Triboelectric Nanogenerators With Rotating Structure

Carbon Energy, EarlyView.
The rotating TENG has been widely studied for its superiorities of simple structure, high efficiency, and stable output. This review introduced the four different principles of rotating TENG and offered a thorough summary for performance and application research through three‐level classification. Importantly, the current existing problems, challenges,
Chuguo Zhang, Chunxu Xue, Yutong Chen, Yujie Qiang, Seeram Ramakrishna   +4 more
wiley   +1 more source

Plant-Derived Medicines for Sciatica: A Comprehensive Review

Traditional and Integrative Medicine
Sciatica commonly refers to radicular leg pain which is mainly caused by lumbar disc herniation (LDH) and affects the daily functional ability of many patients in the world.
Narges Lavari, Niusha Esmaealzadeh, Roja Rahimi, Alireza Abbasian   +3 more
doaj   +1 more source

Combinatorial expression of glial transcription factors induces Schwann cell‐specific gene expression in mouse embryonic fibroblasts

Developmental Dynamics, EarlyView.
Abstract Background Schwann cells provide peripheral nerve trophic support, myelinate axons, and assist in repair. However, Schwann cell repair capacity is limited by chronic injury, disease, and aging. Schwann cell reprogramming is a cellular conversion strategy that could provide a renewable cell supply to repair injured nerves.
Lauren Belfiore, Anjali Balakrishnan, Yacine Touahri, Dawn Zinyk, Humna Noman, Satoshi Okawa, Jeff Biernaskie, Carol Schuurmans   +7 more
wiley   +1 more source