Results 51 to 60 of about 30,872 (288)

Clinical diagnostic model for sciatica developed in primary care patients with low back-related leg pain.

open access: yesPLoS ONE, 2018
BackgroundIdentification of sciatica may assist timely management but can be challenging in clinical practice. Diagnostic models to identify sciatica have mainly been developed in secondary care settings with conflicting reference standard selection ...
Siobhán Stynes   +4 more
doaj   +1 more source

VDAC1 Upregulation Induces Hyperexcitability of Nociceptive Sensory Neurons Via Enhanced Mitochondrial Atp Efflux in Neuropathic Pain

open access: yesAdvanced Science, EarlyView.
The mechanism diagram of VDAC1 mediating neuronal excitability and neuropathic pain. Briefly, VDAC1 is expressed in DRG neurons and is upregulated following CCI‐induced neuropathic pain. This upregulation enhances ATP transport from mitochondria to the cytoplasm in sensory neurons, leading to increased neuronal excitability and pain behavior.
Fengrun Sun   +7 more
wiley   +1 more source

Effect and neurophysiological mechanism of acupuncture in patients with chronic sciatica: protocol for a randomized, patient-assessor blind, sham-controlled clinical trial

open access: yesTrials, 2019
Background Sciatica is a relatively frequent illness that easily becomes a chronic and relapsing condition. Although numerous systematic reviews have analyzed various therapies for sciatica, the validity of their included studies is limited.
Koh-Woon Kim   +11 more
doaj   +1 more source

Low back pain and sciatica in over 16s: assessment and management NICE Guideline [NG59].

open access: yesJournal of Physiotherapy, 2017
Date of latest update: 30 November 2016. Patient group: People aged 16 years and suffering from low back pain and sciatica. Intended audience: Healthcare professionals, commissioners and providers of healthcare, people with low back pain or sciatica and ...
T. D. de Campos
semanticscholar   +1 more source

Harnessing Phase Separation for the Development of High‐Performance Hydrogels

open access: yesAdvanced Science, EarlyView.
ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao   +3 more
wiley   +1 more source

Embracing Homoeopathy: A Paradigm Shift in Pain Management of Sciatica

open access: yesJournal of Clinical and Biomedical Sciences
Increasing reports of sciatica irrespective of age and gender due to lifestyle, genetic or environmental factors. The unbearable pain of sciatica is a major problem interfering with a patient’s life.
Mohnyca Yumnam, Mrinal A Nerlekar
doaj   +1 more source

An Unusual Presentation of Right-Sided Sciatica with Foot Drop

open access: yesCase Reports in Orthopedics, 2016
Rarely, sciatica is of extraspinal aetiology. By compressing the sciatic nerve, swelling of the short external rotators of the hip can cause sciatica.
Fergus J. McCabe, John P. McCabe
doaj   +1 more source

NSAIDs in sciatica (NIS): study protocol for an investigator-initiated multicentre, randomized placebo-controlled trial of naproxen in patients with sciatica

open access: yesTrials, 2022
Background Nonsteroidal anti-inflammatory drugs (NSAIDs) are widely used to treat sciatica, despite insufficient evidence from placebo-controlled trials.
Lars Grøvle   +3 more
doaj   +1 more source

A case report of sciatic hernia as a cause of sciatica and lower back pain: Diagnostic dilemma for family physicians

open access: yesJournal of Family Medicine and Primary Care, 2022
Degenerative changes in lumbosacral spine or disc bulges impinging on the thecal sac are the usual causes of sciatica. However peripheral compression of sciatic nerve in pelvis or lower limb presenting as sciatica is an uncommon entity.
Navdeep Kaur   +4 more
doaj   +1 more source

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