Results 91 to 100 of about 4,214,970 (307)
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Productivity of Nanobiotechnology Research and Education in U.S. Universities [PDF]
The National Science Foundation (NSF) estimates that nanotechnology will become a trillion-dollar industry by 2015 and that 800,000 workers will be needed in this field in the United States.
Xia, Yin
core +1 more source
Model-Tracing Based Approach to Intelligent Program Diagnosis
Model-tracing based approach to intelligent program diagnosis and tutoring emphasizes the fact that the student’s design decisions are traced as the students develops the program Systems based on this model monitor the user's actions as the moves along ...
Haider Ali Ramadhan
doaj +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Filter Representation of Normal Lattice
In this paper we will investigate the properties of normality lattices and their relationships to zero-one measures. We will establish necessary and sufficient conditions for lattices to be normal.
B. Yallaoui
doaj +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Using Switching Linear Systems to Reach a Prespecified Traget
A conventional enumeration approach, and a new approach for the solution of the control of switched linear systems with input constraints are presented. The main objective in this work is to determine control sequences {U‘(K), i -l , M and k –O, l, …..,
A. Benmerzouga
doaj +1 more source
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Elementary metallography [PDF]
Materials and Processes 1 (MET 141) is offered to freshmen by the Mechanical Engineering Department at Purdue University. The goal of MET 141 is to broaden the technical background of students who have not had any college science courses.
Kazem, Sayyed M.
core +1 more source
Cation Distribution in Natural Chromites from Oman
Two specimens or natural chromite from the Oman ophiolite were studied using Mossbauer Spectroscopy (MS), X-ray Diffraction (XRD). and Scanning Electron Microscopy (SEM). The diffraction patterns obtained at room temperature showed that the two specimens
Z. Al-Alawi +7 more
doaj +1 more source

