Results 81 to 90 of about 4,214,970 (307)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Solvent Extraction of Uranium (VI) by Didodecylphosphoric Acid

Sultan Qaboos University Journal for Science, 1999
Solvent extraction of uranium(Vl) ion from perchlorate solution using didodecylphosphorie acid, DDPA, in toluene diluent was studied. The effects of stripping nitric acid concentration, stripping time, extraction time, DDPA concentration, pH, ionic ...
Khaled Mousa, Fawwaz Khalili
doaj   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Endocrine, Physiological and Histopathological Responses of Fish and their Larvae to Stress with Emphasis on Exposure to Crude Oil and Various Petroleum Hydrocarbons

Sultan Qaboos University Journal for Science, 2000
Various endocrine and physiological responses of fish exposed to forceful physical and chemical stimuli are reviewed with emphasis on the effects of crude oils and their hydrocarbon constituents.
A. Y. A. AL-Kindi, J.A. Brown, C.P. Waring   +2 more
doaj   +1 more source

Applied research won’t flourish without basic science

eLife
Three senior figures at the US National Institutes of Health explain why the agency remains committed to supporting basic science and research.
Jon R Lorsch, Lawrence A Tabak, Monica M Bertagnolli   +2 more
openaire   +3 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

The Stratigraphy and Structure of the Madamar-Salakh-Qusaybah Range and Natif-Fahud Area in the Oman Mountains

Sultan Qaboos University Journal for Science, 1996
Melanges and debris flows with clasts derived from the top of the Natih Formation found in shales in the base of the Aruma Group indicate that a period of Structural growth on the platform took place during Aruma deposition in the Late Cretaceous.
S.S. Hanna, J.D. Smewing
doaj   +1 more source

[Basic science and applied science].

Salud publica de Mexico, 2002
A lecture was presented by the author at the Democratic Opinion Forum on Health Teaching and Research, organized by Mexico's National Health Institutes Coordinating Office, at National Cardiology Institute "Ignacio Chavez", where he presented a critical review of the conventional classification of basic and applied science, as well as his personal view
openaire   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Nodulation of Medicago Sativa L. by Different Rhizobium Strains in the Sultanate of Oman

Sultan Qaboos University Journal for Science, 1997
Three native Rhizobium strains were isolated from Musandam. Buraimi and the Agricultural Experiment Station at Sultan Qaboos University in the Sultanate of Oman. An internationally known Rhizobium strain (TAI.
A.E. Elshafie, R. Victor, N. Al-Mugbali
doaj   +1 more source