Results 81 to 90 of about 858,677 (313)

The Stratigraphy and Structure of the Madamar-Salakh-Qusaybah Range and Natif-Fahud Area in the Oman Mountains

open access: yesSultan Qaboos University Journal for Science, 1996
Melanges and debris flows with clasts derived from the top of the Natih Formation found in shales in the base of the Aruma Group indicate that a period of Structural growth on the platform took place during Aruma deposition in the Late Cretaceous.
S.S. Hanna, J.D. Smewing
doaj   +1 more source

[Basic science and applied science].

open access: yesSalud publica de Mexico, 2002
A lecture was presented by the author at the Democratic Opinion Forum on Health Teaching and Research, organized by Mexico's National Health Institutes Coordinating Office, at National Cardiology Institute "Ignacio Chavez", where he presented a critical review of the conventional classification of basic and applied science, as well as his personal view
openaire   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Nodulation of Medicago Sativa L. by Different Rhizobium Strains in the Sultanate of Oman

open access: yesSultan Qaboos University Journal for Science, 1997
Three native Rhizobium strains were isolated from Musandam. Buraimi and the Agricultural Experiment Station at Sultan Qaboos University in the Sultanate of Oman. An internationally known Rhizobium strain (TAI.
A.E. Elshafie, R. Victor, N. Al-Mugbali
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Model-Tracing Based Approach to Intelligent Program Diagnosis

open access: yesSultan Qaboos University Journal for Science, 1997
Model-tracing based approach to intelligent program diagnosis and tutoring emphasizes the fact that the student’s design decisions are traced as the students develops the program Systems based on this model monitor the user's actions as the moves along ...
Haider Ali Ramadhan
doaj   +1 more source

Influence integrated science model and implamantation learning with the unity of science in basic biology course to increase critical thinking

open access: yes, 2017
This research purposed to investigate the effect of  integrated science model and its implementation in learning by Unity of Science in Basic Biology courses to improve students' critical thinking.
Baskoro Baskoro   +7 more
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Filter Representation of Normal Lattice

open access: yesSultan Qaboos University Journal for Science, 1996
In this paper we will investigate the properties of normality lattices and their relationships to zero-one measures. We will establish necessary and sufficient conditions for lattices to be normal.
B. Yallaoui
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

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