Results 101 to 110 of about 858,677 (313)

The Seroprevalence of Human Toxoplasmosis in Oman

open access: yesSultan Qaboos University Journal for Science, 1996
The prevalence of Toxoplasma 1gG antibodies was studied in three age groups (children. blood donors and pregnant women) in Oman. The highest prevalence rate was shown by pregnant women (39.5%).
M.A. Idris   +2 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Applying Halstead's Metric to Oberon Language

open access: yesSultan Qaboos University Journal for Science, 1999
Oberon is a small, simple and difficult programming language. The guiding principle of Oberon was a quote from Albert Einstein: "Make it as simple as possible, but not simpler".
Fawaz Ahmed Masoud
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Industry-science connections in agriculture: Do public science collaborations and knowledge flows contribute to firm-level agricultural research productivity? [PDF]

open access: yes
Prior research shows long-run productivity growth in agriculture is associated with increases in the stock of public scientific knowledge and private patented inventions. However, private inventions may be a function of the stock of public knowledge.
King, John L., Toole, Andrew A.
core  

Science Production in Iran: The Scenario of Iranian Medical Journals [PDF]

open access: yes, 2009
In Iran, the number of published articles has increased significantly in the basic and applied sciences including medicine and its subspecialties during the recent years.
Farzaneh Aminpour   +3 more
core  

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

SHAPING A CONSTRUCTIVIST VIEW OF ORGANIZATIONAL DESIGN SCIENCE [PDF]

open access: yes
The so-called rigor–relevance gap appears unbridgeable in the classical view o organization science, which is based on the physical sciences' model.
M.-J. Avenier
core  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

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