Results 31 to 40 of about 35,582,439 (251)

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

A Computer Aided Learning Tool for Readers

open access: yesSultan Qaboos University Journal for Science, 1999
A bilingual piece of software has been developed to cultivate student speed and critical reading abilities by expanding their visual span, improving their eye movement, reducing their visual regression, developing their stock of vocabulary, and by honing
Sane M Yagi, Saad Harous
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Mycoflora and Mycotoxigenic Moulds of Pistachio Nuts for Human Consumption in the Sultanate of Oman

open access: yesSultan Qaboos University Journal for Science, 1998
Mycoflora of 75 cans of different batches and brands of pistachio nuts purchased in the Sultanate of Oman was studied. A number of fungi were isolated, with percentages of contaminated nuts [average between brands ] as follows: Aspergillus niger 14.8 ...
A. E. Elshafie, N. S. AL-Shally
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Effect of Wind Environment on the response of Buildings in Oman

open access: yesSultan Qaboos University Journal for Science, 1998
An investigation has been carried out to study the effect of the wind parameters on the response of multistory buildings subjected to wind induced forces.
Mohammed Qamaruddin, Salem K. Al-Oraimi
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Ghost Crabs of Oman ( Crustacea : Brachyura :Ocypodidae)

open access: yesSultan Qaboos University Journal for Science, 1996
The sandy beaches of the coasts of Oman support five species of Ocypode ghost crabs.  Ocypode cordimanus is found on supra-littoral sand dunes while O. saratan O. rotundata, and O. platytarsis  occur on the open beaches. O.
D.A. Clayton
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Distributed Simulation of Open Cyclic Queuing Networks

open access: yesSultan Qaboos University Journal for Science, 1997
In this paper we present the results of an experimental performance study of distributed simulation of open cyclic queuing networks using a minor variation of the deadlock detection and recovery based algorithm of Chandy and Misra. One major part of this
Saad Harous
doaj   +1 more source

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