Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Does a generous welfare state crowd out student effort? Panel data evidence from international student tests. [PDF]
Student achievement has been identified as an important contributor to economic growth. This paper investigates the hypothesis that redistributive government activities have a negative effect on investment in human capital using data from international ...
Falch, Torberg, Fischer, Justina AV
core
What Does the NAEP Tell Us About Student Achievement in Arkansas? [PDF]
This brief discusses the most recent and historical NAEP data in math, science, reading, and writing. Arkansas’ NAEP results are compared to national and border state averages.
Barnett, Joshua H., Ritter, Gary W.
core +2 more sources
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Pengaruh Implementasi Metode Mind Mapping Terhadap Hasil Belajar IPS Ditinjau Dari Minat Siswa Kelas IV SD Sathya Sai Denpasar [PDF]
This study aimed at investigating the effect of the implementation of mind mapping learning method to the students' social science achievement viewed from learning interest at the fourth grade students of SD Sathya Sai in the academic year of 2012/2013 ...
Darmayoga, I. W. (I) +2 more
core
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
The relationship between non-cognitive student attributes and academic achievements in a flipped learning classroom of a pre-dental science course [PDF]
Minsun Kim, Sangho Roh, Jungjoon Ihm
openalex +1 more source
Mathematica's Evaluation of The Equity Project Charter School: High Salaries for Teachers, Positive Impacts on Student Achievement [PDF]
Mathematica found that by the end of the 2012 -- 2013 school year, TEP's impacts on student achievement were consistently positive across subjects and cohorts, with especially large effects in math. Using benchmarks for average annual learning gains, the
Brian Gill +2 more
core
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source

