Results 231 to 240 of about 1,558,680 (346)

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

How social-emotional learning promotes reading achievement? A systematic review of mechanisms and instructional design. [PDF]

Front Psychol
Hua L, Zhang Z, Wang H.
europepmc   +1 more source

Educational factors influencing academic achievement in biomedical sciences among undergraduate nursing students in Uganda: analytical cross-sectional study [PDF]

Clement Munguiko, Anne Ngeno, Safinah Kisu Museene   +2 more
openalex   +1 more source

Momentary emotion profiles in high school science and their relations to control, value, achievement, and science career intentions.

, 2020
Kristy A. Robinson, Patrick N. Beymer, John Ranellucci, Jennifer Schmidt   +3 more
openalex   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Achievement emotion in war victim children: A study on Syrian primary and secondary school students in Turkey. [PDF]

Glob Ment Health (Camb)
Sarac E, Bektas F, At E, Karadag E, Ciftci SK.   +4 more
europepmc   +1 more source

The Effects of Roleplaying-Oriented STS Lessons on High School Students' Attitudes Related to Science and Knowledge Achievement for Understanding Biodiversity

, 2009
김동렬
openalex   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Configurational impact of motivational factors on postdoctoral job satisfaction. [PDF]

Sci Rep
Bing X, Wan X.
europepmc   +1 more source

The Impact of Using Elementary Science Specialists on 5th Grade Science Achievement Scores

, 2019
Wesley Armstrong Roach
openalex   +1 more source