Results 91 to 100 of about 6,304,582 (340)
Science, technology and society for our century [inaugural lecture, 16 April 2013] [PDF]
, 2013 The links between science and technology, on the one hand, and wider society, on the other, have been the focus of growing attention over the past two generations.
Johnston, S.F.
core
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Extreme vacuum technology including cryosorption, diffusion pump and pressure calibration studies Summary technical report, 1 Feb. 1965 - 1 Mar. 1966 [PDF]
Cryosorption, diffusion pump, and pressure calibration studies in extreme vacuum science and technology application ...
Bryant, P. J., Gosselin, C. M.
core +1 more source
FEBS Letters, EarlyView.At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom +3 more
wiley +1 more source
, 2006 Constructivism has become the overarching scientific paradigm in the social study of science and technology (STS). The notion that scientific facts and technological artefacts result from processes of social construction is the major scientific ...
Böschen, Stefan +4 more
core
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Critiques protocolaires d’Internet : comparaison des projets IPFS et SecureScuttleButt
Tic & SociétéThis article highlights the political a priori and debates around two critical infrastructures proposed as alternatives to current Internet protocols: the IPFS (Interplanetary File System) and SSB (SecureScuttlebutt). Using critical discourse analysis to
Pierre DEPAZ
doaj +1 more source
Preserving Communication Context. Virtual workspace and interpersonal space in Japanese CSCW. [PDF]
, 1998 The past decade has seen the development of a perspective\ud holding that technology is socially constructed (Mackenzie and Wacjman, 1985; Bijker, Hughes and Pinch, 1987; Bijker and Law, 1992).
Heaton, Lorna
core +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source