Results 81 to 90 of about 2,052,459 (259)

Science and Technology Studies and Affect in the Wild

Zygon
Expanding on comments made at last year’s Society for Social Studies of Science (4S) Meeting on a panel recognizing Donovan Schaefer’s Wild Experiment as the winner of the Fleck Prize, this article explores the book’s adjacencies in order to tell a “wild”
Mathew Arthur
doaj   +2 more sources

The technological paradigm of Nanosciences and Technologies: a study of science-technology time and space relations

Economía Teoría y Práctica, 2013
One of the most relevant theoretical insights into the characteristics of technological change is Dosi's technological paradigm. Dosi aims to overcome technology's push and demand-pull theories into a framework closer to facts. The present contribution is set in this framework, aiming to find some evidence, starting from an empirical analysis, of the ...
openaire   +5 more sources

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Interpretive ethnographic studies and in-depth qualitative research should be treated as high-quality evidence in the science of team science

Frontiers in Psychology
The Science of Team Science (SciTS) has an evidence problem. On the one hand, there are few studies demonstrating the effectiveness of evidence-informed team science trainings.
Stephen Molldrem, Stephen Molldrem, Kevin Wooten, Kevin Wooten   +3 more
doaj   +1 more source

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

FEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez, Mikael Oliveberg, Peter Brzezinski   +2 more
wiley   +1 more source

Critiques protocolaires d’Internet : comparaison des projets IPFS et SecureScuttleButt

Tic & Société
This article highlights the political a priori and debates around two critical infrastructures proposed as alternatives to current Internet protocols: the IPFS (Interplanetary File System) and SSB (SecureScuttlebutt). Using critical discourse analysis to
Pierre DEPAZ
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Machinery of dissent: Exploring the techno-social practices of modern protests

Internet Policy Review
Protest mobilisation and coordination require competences that extend beyond political leadership and communication. Technology, which has become a daily part of humanity, pushes protest leaders to obtain skills in navigating social media to achieve ...
Alesia Rudnik
doaj   +1 more source