Results 61 to 70 of about 2,052,459 (259)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Debugging the Techno-Utopian Myth of Predictive Policing

Journal of Extreme Anthropology, 2021
Kira Vrist Rønn
doaj   +1 more source

Improving the agri-food biotechnology conversation: bridging science communication with science and technology studies. [PDF]

Agric Human Values, 2023
Broad GM.
europepmc   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Consumer Preferences and Willingness to Pay for Vertiport Design, Amenities, and Services

International Journal of Aviation, Aeronautics, and Aerospace
The rise of urban air mobility (UAM) and electric vertical takeoff and landing (eVTOL) aircraft necessitates the development of well-designed vertiports that align with consumer expectations.
David C. Ison
doaj   +1 more source

ST(&)S: Martyn Pickersgill Talks with Sheila Jasanoff

Engaging Science, Technology, and Society, 2018
In this interview, Sheila Jasanoff and Martyn Pickersgill discuss the contested meanings of STS, defined as either “science and technology studies” (often associated with European origins) or “science, technology, and society” (commonly seen as ...
MARTYN PICKERSGILL1, SHEILA JASANOFF
doaj   +1 more source

Cultivating intellectual community in academia: reflections from the Science and Technology Studies Food and Agriculture Network (STSFAN). [PDF]

Agric Human Values, 2023
Burch K, Gugganig M, Guthman J, Reisman E, Comi M, Brock S, Kagliwal B, Freidberg S, Baur P, Heimstädt C, Sippel SR, Speakman K, Marquis S, Argüelles L, Biltekoff C, Broad G, Bronson K, Faxon H, Frohlich X, Ghosh R, Halfon S, Legun K, Martin SJ.   +22 more
europepmc   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

What fiction does within and outside technoscience: Science fiction, fictional technofutures, and sociotechnical fictions

TATuP – Zeitschrift für Technikfolgenabschätzung in Theorie und Praxis
This article examines how fiction works within and outside technoscience by comparing three interrelated concepts: science fiction, fictional technofutures, and sociotechnical fictions.
Andreu Belsunces Gonçalves, Wenzel Mehnert   +1 more
doaj   +1 more source