Results 41 to 50 of about 2,408,246 (297)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Shaping knowledge through exhibitions: curating in Art, Science, and Technology Studies
ArtnodesMultidisciplinary exhibitions are all around us: in science centres, technology museums, contemporary art galleries, national museums and natural history museums.
Hannah Star Rogers
doaj +1 more source
The future, the foreign and the public–private divide: Socio-political discourses around Skolkovo
Journal of Eurasian Studies, 2014 This article takes an in-depth look at the establishment of a technology and educational complex outside of Moscow dedicated to promoting innovation.
Elana Wilson Rowe
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Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
The Floating Ampersand: STS Past and STS to Come
Engaging Science, Technology, and Society, 2016 STS has become a discipline in the sense that it offers new ways to read and make sense of the world. It remains an amalgam, however, of two linked yet separate lines of inquiry, both abbreviated as STS.
Sheila Jasanoff
doaj +1 more source
The production of laboratory scientists: Negotiating membership and (re)producing culture
Frontiers in Education, 2022 This ethnographic work is about the recruitment and enculturation of novice scientists in the laboratory. Interviews and participant observation were conducted in a biochemistry research lab at a small liberal arts college.
Yifan Zhang, Yifan Zhang
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Science and technology studies: Exploring the knowledge base [PDF]
Research Policy, 2012 One of a number of new research fields to emerge over the last four or five decades is Science and Technology Studies (STS). This paper attempts to identify the core contributions to this emerging field. Following the methodology developed by Fagerberg and Sapprasert (2010) in their parallel study of Innovation Studies, it adopts the perspective of the
R. Martin, Ben +2 more
openaire +6 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Translating science in the 18th and 19th centuries : interdisciplinary perspectives [PDF]
This book explores the role of translation in shaping the knowledge-sharing processes that were and are seminal to scientific endeavour. It considers the mechanisms by which eighteenth- and nineteenth-century European science writing travelled within and
Pickford, Susan, Martin, Alison E
core +1 more source