Results 151 to 160 of about 2,250,027 (306)
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Modernism, Science, and Technology
Intro -- Title Page -- Copyright Page -- Contents -- Acknowledgments -- Chapter 1 Modernist culture, modernist science -- Science in transition -- Tools for modernist studies -- New modernist studies, science, and technology -- Two cultures?
Morrisson, Mark S. +2 more
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Matrices of science and technology interactions: implications for development [PDF]
Scientific and other non-patent references (NPRs) in patents are important tools to analyze interactions between science and technology. This paper organizes a database with 514,894 USPTO patents granted globally in 1974, 1982, 1990, 1998 and 2006. There
Américo Tristão Bernardes +3 more
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Circus, Science and Technology: Dramatising Innovation
, 2020 This book explores the circus as a site in and through which science and technology are represented in popular culture. Across eight chapters written by leading scholars - from fields as varied as performance and circus studies, art, media and cultural ...
Jurgens, Anna-Sophie
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Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Computer approaches for the handling of large social science data files
, 1967 Statement of responsibility on cover reads: Ithiel de Sola Pool, James M. Beshers, Stuart McIntosh, and David GriffelCover title"January 1967.""1687"--handwritten on coverA progress report to the National Science Foundation GS ...
McIntosh, Stuart D. +3 more
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Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Studies of the purine biosynthetic pathways in the gastrointestinal tract.
, 1979 Thesis (Ph.D.)--Massachusetts Institute of Technology, Dept. of Nutrition and Food Science, 1979.MICROFICHE COPY AVAILABLE IN ARCHIVES AND SCIENCE.Vita.Bibliography: leaves 203-213.Ph ...
LeLeiko, Neal Simon
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South Atlantic science and technology studies: histories and practices
Tapuya, 2022 Breny Mendoza, Sandra Harding
doaj +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source