Results 71 to 80 of about 14,512,132 (358)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Spotlight on Earth Science Symposium: An Overview [PDF]

open access: yes, 2008
On September 18-19, 2006, James Madison University (JMU) hosted a one and half day symposium entitled, “Spotlight on Earth Science,” highlighting current resources and technology available for earth science teachers, and invited teachers to share ...
Pyle, E.
core   +1 more source

Building an Argument for the Use of Science Fiction in HCI Education

open access: yes, 2018
Science fiction literature, comics, cartoons and, in particular, audio-visual materials, such as science fiction movies and shows, can be a valuable addition in Human-computer interaction (HCI) Education. In this paper, we present an overview of research
C Vrasidas   +10 more
core   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Education Science, Humanities Search Synergistic Technologies of Education

open access: yesНаука. Инновации. Технологии, 2022
This paper presents a brief analysis of the synergy humanitarian search technology education from the standpoint of the requirements of the problems of formation and development of modern Education science.
Irina Viktorovna Burkina
doaj  

Curriculum development in integrated science for form one to form three in Mauritius : a thesis presented in partial fulfilment of the requirements for the degree of Master of Philosophy at Massey University [PDF]

open access: yes, 1981
During the past decade, Integrated Science curricula and courses have mushroomed all over the world. Likewise the Mauritius Integrated Science Project came into existence in 1976. Implied is that this 'new' science course is also a 'better' course. Is it
Sin Yan Too, Chin Hin
core  

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Using Technology to Enhance Pre-Service Teacher Preparation [PDF]

open access: yes, 2000
Use of the internet to deliver a portion of the content in an introductory science, education, and technology methods course for pre-service teachers provides an opportunity for a much needed introduction to basic computer literacy.
Miele, E.
core   +1 more source

Science Education for Citizenship and a Sustainable Future [PDF]

open access: yes, 2003
In this article Jerry Wellington argues very strongly in favour of the role of science in citizenship education. He emphasizes the need for knowledge, skills and action and suggests areas and ways in which pupils can be engaged in the struggle for a ...
Allen T.   +7 more
core   +1 more source

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