Results 81 to 90 of about 2,279,526 (315)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

A pedagogical tool for science teacher education: Content Representation (CoRe) design

, 2010
The promotion of reflective practice amongst participants in teacher education programmes (e.g. Bain et al, 1999; Moon, 1999; Loughran & Corrigan, 1995; Shireen et al, 2003; Wallace & Louden, 2003) and the wider teaching community is widely championed ...
Hume, Anne Christine
core  

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Other title: Science Education Standards

, 2001
"Adopted February 14, 2001" Includes bibliographical references."The educational system must prepare the citizens of Kansas to meet the challenges of the 21st century.
Kansas. State Board of Education.
core  

Taking ownership: The story of a successful partnership for change in a Pacific Island science teacher education setting.

, 2011
This paper explores an example of a partnership approach that appears to be producing sustainable change in a Pacific Islands education setting. The people involved report on the way science education staff from the Solomon Islands School of Education ...
Pita, Solomon, Solomon Pita, Porakari, James, Edwards, Richard, James Porakari, Richard Edwards   +5 more
core   +1 more source

Data-Rich Science Instruction: Current Practices and Professional Learning Needs for Middle and High School Earth Science

Education Sciences
Data fluency—the ability and confidence to actively make sense of and use data—is increasingly recognized as essential for students’ civic participation and scientific literacy, yet questions remain about implementing data-rich instruction effectively ...
Nicole Wong, Rasha Elsayed, Leticia R. Perez, Katy Nilsen, Kirsten R. Daehler, Svetlana Darche   +5 more
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

The Uses of the Term Hypothesis and the Inquiry Emphasis Conflation in Science Teacher Education

, 2011
International audienceThis paper examines the use and role of the term 'hypothesis' in science teacher education as described by teacher students. Data was collected through focus group interviews conducted at seven occasions with 32 students from six ...
Gyllenpalm, Jakob, Gyllenpalm, Jakob,, Wickman, Per-Olof, Jakob Gyllenpalm, Per‐Olof Wickman, Wickman, Per-Olof,   +5 more
core   +1 more source

Usable STEM: Student Outcomes in Science and Engineering Associated with the Iterative Science and Engineering Instructional Model

Education Sciences
While our world consistently presents complicated, interdisciplinary problems with STEM foundations, most pre-university curricula do not encourage drawing on multidisciplinary knowledge in the sciences and engineering to create solutions.
Nancy B. Songer, Julia E. Calabrese, Holly Cordner, Daniel Aina   +3 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source