Results 61 to 70 of about 10,899,612 (352)

FoxO1 signaling in B cell malignancies and its therapeutic targeting

open access: yesFEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac   +3 more
wiley   +1 more source

Studi Korelasi Pengetahuan Sains dan Sikap Terhadap Sains di SMA Santo Paulus Pontianak

open access: yesPendipa, 2022
Indonesian education currently focuses on improving 21st-century skills, one of which is scientific literacy. This study aims to provide information related to the profile of general science knowledge and attitudes towards science and the relationship ...
Suliono Suliono   +2 more
doaj   +1 more source

Public knowledge about polar regions increases while concerns remain unchanged [PDF]

open access: yes, 2012
The authors of this brief conduct the first comparative analysis of the polar questions that were part of the National Opinion Research Center\u27s 2006 and 2010 General Social Survey.
Cutler, Matthew J.   +2 more
core   +1 more source

The epistemic predicament of a pseudoscience: social constructivism confronts Freudian psychoanalysis [PDF]

open access: yes, 2011
Social constructivist approaches to science have often been dismissed as inaccurate accounts of scientific knowledge. In this paper, we take the claims of robust social constructivism seriously and attempt to find a theory which does instantiate the ...
Boudry, Maarten, Buekens, Filip
core   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Emotional responses to innovative Science teaching methods: Acquiring emotional data in a General Science teacher education class

open access: yesJournal of Technology and Science Education, 2018
The current work tries to inquiry how different teaching methods affect on the student’s emotional performance. The traditional questionnaire for data collection has been replaced by in-situ, on-line-assisted, survey.
Jesus Sanchez-Martin   +2 more
doaj   +1 more source

Science collaboration networks in sociology and their general characteristics in Serbia [PDF]

open access: yesSociološki Pregled, 2012
Science collaboration networks occupy an important place in the analysis of social networks. There are several directions of concern in this kind of research: one attempts to explain the structure of science collaboration networks, the second one ...
Lazar Zsolt, Sokolovska Valentina
doaj   +1 more source

A stepwise emergence of evolution in the RNA world

open access: yesFEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

Equilibrium problems on Riemannian manifolds with applications [PDF]

open access: yes, 2018
We study the equilibrium problem on general Riemannian manifolds. The results on existence of solutions and on the convex structure of the solution set are established.
Li, Chong   +3 more
core   +1 more source

Evolutionary interplay between viruses and R‐loops

open access: yesFEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi   +4 more
wiley   +1 more source

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