Results 81 to 90 of about 21,085,562 (347)
Identification of novel small molecule inhibitors of ETS transcription factors
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla+9 more
wiley +1 more source
Redesigning a General Education Science Course to Promote Critical Thinking
Traditional general education science courses appear ineffective at helping students improve their critical-thinking skills and engage with discomforting topics (e.g., evolution).
Matthew P. Rowe+5 more
semanticscholar +1 more source
The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum
In Saccharomyces cerevisiae, Yeast Amino acid Transporter family members mediate the import of amino acids, ranging from substrate specialists to generalists. Here, we show that the specialist transporter, Lyp1, has a broader substrate spectrum than previously described, with affinity constants spanning from micromolar to millimolar.
Foteini Karapanagioti+3 more
wiley +1 more source
How the General Public Appraises Contributory Citizen Science: Factors that Affect Participation
Understanding the factors that affect participation plays a crucial role in the success of any contributory citizen science project. We focus our study on the general public, who most likely have not participated in citizen science before, since they ...
Khoi Manh Ngo+2 more
doaj +1 more source
Science with the X-ray Imaging and Spectroscopy Mission (XRISM) [PDF]
This white paper was prepared by members of the XRISM Science Team for the benefit of the general astronomical community. This paper describes the capabilities of XRISM, offers a sampling of the many science topics that the mission will address, and discusses the synergies of XRISM with the plethora of planned and existing facilities in the 2020s and ...
arxiv
The 4+1 Model of Data Science [PDF]
Data Science is a complex and evolving field, but most agree that it can be defined as a combination of expertise drawn from three broad areascomputer science and technology, math and statistics, and domain knowledge -- with the purpose of extracting knowledge and value from data.
arxiv
Social context prevents heat hormetic effects against mutagens during fish development
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere+5 more
wiley +1 more source
Towards a systemic research methodology in agriculture: Rethinking the role of values in science [PDF]
The recent drastic development of agriculture, together with the growing societal interest in agricultural practices and their consequences, pose a challenge to agricultural science.
Alrøe, Hugo Fjelsted+1 more
core
We describe an introductory data science course, entitled Introduction to Data Science, offered at the University of Illinois at Urbana-Champaign.
Brunner, Robert J., Kim, Edward J.
core +2 more sources
The current work tries to inquiry how different teaching methods affect on the student’s emotional performance. The traditional questionnaire for data collection has been replaced by in-situ, on-line-assisted, survey.
Jesus Sanchez-Martin+2 more
doaj +1 more source