Results 81 to 90 of about 20,984,995 (345)

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

The Sunrise Mission [PDF]

, 2010
The first science flight of the balloon-borne \Sunrise telescope took place in June 2009 from ESRANGE (near Kiruna/Sweden) to Somerset Island in northern Canada.
A. Feller, A. Gandorfer, A. Gandorfer, A. Lecinski, A. López Jiménez, A. M. Title, A. Sanz-Andrés, A. Watt, A. Álvarez-Herrero, B. Chares, B. Grauf, B. W. Lites, C. Widani, D. Elmore, D. Germerott, D. Kampf, D.M. Rust, E. Schmidt, G. Card, G. Tomasch, I. Pérez-Grande, I. Pérez Grande, J. A. Bonet, J. C. del Toro Iniesta, J. Fox, J. Hirzberger, J. Hirzberger, J. L. Gasent Blesa, J.P. Mehltretter, K. Heerlein, K. Härtel, L. Sabau-Graziati, M. Herse, M. Knölker, M. Kolleck, M. Schwarzschild, M. Schüssler, P. Barthol, P. Haberler, P. Lemaire, P. Lemaire, P. Nelson, P.N. Bernasconi, P.N. Bernasconi, R. Meller, R. Müller, R. Summers, R.E. Danielson, S. K. Solanki, S.K. Solanki, T. Berkefeld, T. Berkefeld, T. Hirayama, T. L. Riethmüller, T. Levin, T.L. Riethmüller, V. Domingo, V. Martínez Pillet, V. Martínez Pillet, V.A. Krat, W. Curdt, W. Deutsch, W. Schmidt   +62 more
core   +4 more sources

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

A personalist-phenomenological model of general resurrection in light of current science and medicine [PDF]

, 2018
I have argued that the central Christian doctrine of general resurrection (with particular reference to the Pauline corpus) can and should be understood in a scientifically and philosophically informed context, and have proposed a personalist ...
Danielyan, Edgar
core  

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, Volume 19, Issue 12, Page 3784-3805, December 2025.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

3308 Training KL2 Scholars to Communicate Science to a General Audience

Journal of Clinical and Translational Science, 2019
OBJECTIVES/SPECIFIC AIMS: Verbal communication is a critical component for professional development and leadership. Yet, many clinical translational scientists lack the skills in communication of their scientific work in a meaningful and exciting manner ...
Cynthia Ann Carnes, John W. Christman, Mark Damian Wewers, Stuart D Hobbs, Rebecca Jackson   +4 more
doaj   +1 more source

Investigating scientific literacy: Scientist’s habits of mind as evidenced by their rationale of science and religious beliefs [PDF]

, 2006
Science and technology have been incredibly success¬ful in purely technical terms. For instance, international air travel, space flight, and curing of hitherto untreatable medical illnesses all are now routine events.
Coll, Richard K., Lay, Mark C., Mark C., Neil   +2 more
core  

Quantum Communication [PDF]

, 2007
Quantum communication, and indeed quantum information in general, has changed the way we think about quantum physics. In 1984 and 1991, the first protocol for quantum cryptography and the first application of quantum non-locality, respectively, attracted
A Acin, A Aspect, A Einstein, A Furusawa, A Muller, AJ Miller, AK Ekert, AL Alexander, B Gisin, B Julsgaard, B Kraus, B Kraus, BC Jacobs, C Gobby, C Langrock, C Peng, C Schuck, CH Bennett, CH Bennett, CH Bennett, CW Chou, D Bethune, D Boschi, D Bouwmeester, D Collins, D Collins, D Deutsch, D Gottesman, D Stucki, D Stucki, E Diamanti, E Schrödinger, E Waks, F Grosshan, G Brassard, G Ribordy, G Weihs, GN Gol'tsman, H Buhrman, H de Riedmatten, H Inamori, H Takesue, H Weinfurter, H Zbinden, H-K Lo, HJ Briegel, I Csiszár, J Brendel, J Van Houwelingen, J Volz, J-W Pan, JD Franson, JF Clauser, JS Bell, K Inoue, LM Duan, M Aspelmeyer, M Bourennane, M Riebe, M Zukowski, MA Rowe, MD Barrett, MD Eisaman, N Gisin, N Gisin, N Gisin, N Gisin, N Lütkenhaus, Nicolas Gisin, P Tamarat, P Townsend, PG Kwiat, PW Shor, R Hughes, Rob Thew, RT Thew, S Pellegrini, S Popescu, S Tanzilli, SL Braunstein, SL Braunstein., T Chanelière, T Cover, T Jennewein, UM Maurer, V Makarov, V Scarani, W Tittel, W-Y Hwang, X-B Wang, Y-H Kim   +90 more
core   +3 more sources

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, Volume 19, Issue 12, Page 3665-3684, December 2025.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

Confidence and loose opportunism in the science classroom : towards a pedagogy of investigative science for beginning teachers [PDF]

, 2006
This paper attempts to establish a conceptual basis on which beginning teachers may be introduced to investigative science teaching in a way that accommodates the teacher voice.
McNally, Jim
core   +1 more source