Results 61 to 70 of about 17,038,828 (311)

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson   +3 more
wiley   +1 more source

Applications of AFM in pharmaceutical sciences [PDF]

open access: yes, 2016
Atomic force microscopy (AFM) is a high-resolution imaging technique that uses a small probe (tip and cantilever) to provide topographical information on surfaces in air or in liquid media.
Lamprou, Dimitrios, Smith, James R.
core   +2 more sources

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski   +9 more
wiley   +1 more source

Missions de l’éducation scientifique et technique

open access: yesRevue Internationale d’Éducation de Sèvres, 2000
Science and technology have become the driving forces in social and economic change in modern society. The teaching of these subjects for all is thus a key prerequisite for citizenship insofar as it contemplates individuals’ relationship with knowledge ...
Jean-Louis Martinand
doaj   +1 more source

On biotechnology, theology, and the human sciences [PDF]

open access: yes, 2018
There may be very good Christian theological reasons to oppose human biotechnological enhancement. It is, however, difficult to discern what they are. Much of the specifically Christian response to transhumanist biotechnological enhancement has revolved ...
Jong, Jonathan
core   +1 more source

Development of science LKPD based on inquiry training on HOTS-science literacy skills

open access: yesInovasi Kurikulum
LKPD circulating in schools mostly does not contain experiments, demonstrations or discussions. This research aims to produce worksheets for students as teaching materials used in the science learning process, thereby creating maximal learning activities
Dini Rozali   +2 more
doaj   +1 more source

Pour une nouvelle formation

open access: yesRevue Internationale d’Éducation de Sèvres, 2000
The arrival of a new generation of teachers should provide an opportunity to overhaul teacher-training systems and extend training throughout teachers’ careers.
Goéry Delacôte
doaj   +1 more source

Preferences of Pediatric Patients and Their Caregivers for Chemotherapy‐Induced Nausea and Vomiting Control Endpoints: A Mixed Methods Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Although not always achieved, complete chemotherapy‐induced nausea and vomiting (CINV) control is the conventional goal of CINV prophylaxis. In this two‐center, mixed‐methods study, we sought to understand the preferences of adolescent patients and family caregivers for CINV control endpoints.
Haley Newman   +8 more
wiley   +1 more source

Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul   +13 more
wiley   +1 more source

Les modalités du temps chez Benjamin Franklin

open access: yesTransatlantica, 2010
The long-lasting fame of Benjamin Franklin rests principally on his characteristics as a scientist and a philosopher of the Enlightenment. This article raises the question of Franklin's conception of time and examines his numerous uses of « time » as a ...
Elise Marienstras
doaj   +1 more source

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