Results 111 to 120 of about 6,354,899 (321)
Drug Repurposing for Treating NCOR‐Related Intellectual Disability
Advanced Science, EarlyView.An autism‐associated NCOR1 heterozygous mutation upregulates NRGs and activates NRG backward signaling in hypothalamic GABAergic neurons in mouse models, leading to Gabra2 downregulation and cognitive deficits, which can be therapeutically targeted by repurposing FDA‐approved drugs.
Yan Kong +15 more
wiley +1 more source
Federal advisory committees ... annual report of the President, covering the calendar year ...
Description based on: 9th (1980); title from cover.Mode of access: Internet.Vol. for 1972 issued by U.S. Office of Management and Budget.Summary of the separately issued report: Federal advisory committees annual report of the President to the Congress ...
United States. Office of Management and Budget. +1 more
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Regional Fisheries Advisory Committee 2nd May, 1978
, 1978 This is the report from the Regional Fisheries Advisory Committee meeting, which was held on the 2nd May 1978. The report contains the minutes of the last meetings of the Local Fisheries Advisory Committees, income and expenditure and the enforcement of ...
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Advanced Science, EarlyView.A blue‐light‐crosslinked bilayer hydrogel was developed for local optic nerve repair. The adhesive GM‐Odex outer layer seals and anchors the lesion, while the non‐adhesive GM‐imid inner layer releases MPDA‐Cle without obstructing CSF flow. This system modulates oxidative and inflammatory microenvironments, supports oligodendrocyte differentiation and ...
Tonghe Pan +13 more
wiley +1 more source
Regional Fisheries Advisory Committee 15th February, 1979
, 1979 This is the report from the Regional Fisheries Advisory Committee meeting, which was held on the 15th February 1979. The report contains the minutes of the last meetings of the Local Fisheries Advisory Committees, information on the long term objectives ...
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Advanced Science, EarlyView.Lactate accumulation after SCI promotes H4K12la lactylation, which upregulates NDUFS7, triggering mitochondrial RET and ROS, enforcing pro‐inflammatory microglial polarization. MM@mPTC, a biomimetic nanotherapeutic, degrades LDHA in activated microglia, reducing H4K12la lactylation and blocking RET, thus curbing ROS, fostering a reparative phenotype ...
Chenglong Hong +13 more
wiley +1 more source
Regional Fisheries Advisory Committee 10th November, 1980
, 1980 This is the report from the Regional Fisheries Advisory Committee meeting, which was held on the 10th November 1980.The report contains sections on the proceedings of Local Fisheries Advisory Committees, netting of Flimby Beach, the closure of Preston ...
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Advanced Science, EarlyView.The study integrates density functional theory with radiochemical and biological validation to compare DOTA‐, PSC‐, and DOTAM‐based chelator‐conjugates for 203Pb/212Pb theranostic applications. Distinct differences in metal coordination, electrostatic properties, conformational flexibility, cellular uptake, biodistribution, and dosimetry are identified
Jeongyun Kim +12 more
wiley +1 more source
Regional Fisheries Advisory Committee 2nd February, 1981
, 1981 This is the report from the Regional Fisheries Advisory Committee meeting, which was held on the 2nd February 1981.The report contains sections on the proceedings of the Local Fisheries Advisory Committee and recommendations for these committees ...
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Advanced Science, EarlyView.To better characterize an infusible extracellular matrix (iECM) material, we applied size‐based fractionation to separate out components into two major fractions. We characterized these fractions to understand how material properties such as composition, morphology, and biochemical properties affect bioactive effects in the context of acute myocardial ...
Michael B. Nguyen +13 more
wiley +1 more source