Results 151 to 160 of about 3,852,365 (305)

Hypotheses, evidence and relationships: The HypER approach for representing scientific knowledge claims [PDF]

open access: yes, 2009
Biological knowledge is increasingly represented as a collection of (entity-relationship-entity) triplets. These are queried, mined, appended to papers, and published.
Buckingham Shum, S.   +5 more
core   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

open access: yesMolecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard   +12 more
wiley   +1 more source

The Ukrainian Neorealism: Evolution of Scientific and Artistic Discourse [PDF]

open access: yes, 2016
У дисертації досліджено художню систему українського неореалізму, який розглядається як течія модернізму, котра актуалізує реалістичний тип творчості. Обґрунтовується правомірність розгляду прозової творчості письменників «Ланки» як зразка неореалізму.
Жигун, Сніжана Віталіївна
core  

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

THE READINESS OF FUTURE FOREIGN LANGUAGE TEACHERS TO SELF-EDUCATION ACTIVITY: THE THEORETICAL METHODOLOGICAL SUBSTANTIATION

open access: yesОсвітологічний дискурс, 2014
The theoretical methodological substantiation of the readiness of future foreign language teachers to self-education activity was represented in the article.
Nataliia S. Chernihivska
doaj  

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

The alphabet of happenstance. On M. L. Gasparov’s Notes and excerpts. Pt. 1.

open access: yesСлово.ру: балтийский акцент, 2015
This article examines the new genre created by L. M. Gasparov — the ‘interdiscursive novel’. The author analyses characteristics of the genre, in particular, its termhood, research features, flexible interaction with methodology, and journalistic style ...
Isaev S.
doaj  

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

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