Results 131 to 140 of about 92,781 (302)
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Pragmatics of Scientific Technical Vocabulary Communication
Today science is the major source of new concepts and consequently scientific technical vocabulary is the largest and the most intensively developing part of contemporary language.
Iļinska, Larisa, Smirnova, Tatjana
core
Intertextuality in Scientific Texts
, 2017 Any text is indebted to other texts, and there is nothing new in the space of intertextual meaning. Every text is inherently intertextual: it incorporates elements of other texts for a specific purpose. Intertextuality considers the text as a fabric or a
Dmitrichenkova, Svetlana +1 more
core +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Learning to write scientific discourse
, 2000 Master of EducationThis thesis describes the perceptions of a group of first year science students about writing tasks during first semester of their tertiary studies. Questionnaires and interviews were used to collect data from students.
Barker, Gayle
core
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Common Scientific Lexicon for Automatic Discourse Analysis of Scientific and Technical Texts [PDF]
, 2008 The paper reports on preliminary results of an ongoing research aiming at development of an automatic procedure for recognition of discourse-compositional structure of scientific and technical texts, which is required in many NLP applications.
Bolshakova, Elena
core
Освітологічний дискурс, 2014 The theoretical methodological substantiation of the readiness of future foreign language teachers to self-education activity was represented in the article.
Nataliia S. Chernihivska
doaj
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source