Results 111 to 120 of about 92,781 (302)
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Problems with the critical posture? Foucault and critical discourse analysis
, 2006 This paper provides a brief analysis of Michel Foucault’s work on power and governmentality, and mounts the argument that the treatment of these concepts by Foucault is theoretical rather than empirical or historical.
Kendall, G., Wickham, G.
core
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Global capitalism and critical awareness of language. [PDF]
, 1999 As the shape of the new global social order becomes clearer, so too does the need for a critical awareness of language as part of language education. I discuss, with a focus on discourse, several key features of late modern society which help make the ...
Fairclough, Norman, Norman Fairclough
core
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
The organization and logic of doctrinary discourse
Bucharest Working Papers in Linguistics, 2007 The purpose of this paper is to point out the main characteristics of doctrinary discourse in terms of structure and organization, as well as the type of argumentation used (conventions, subject matter, persuasive techniques), emphasizing the ...
Maria Nicolescu
doaj
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
CFP: 7th Critical Approaches to Discourse Analysis across Disciplines Conference (CADAAD)
, 2017 4-6 July 2018, Aalborg University, Denmark CADAAD conferences are intended to promote current directions and new developments in cross-disciplinary critical discourse research.
Johanna Meyer
core
Scientific discourse: allocation, functions and genre forms
, 2022 В статті розглянуто науковий дискурс, який є семантично щільною спеціалізованою мовою, оскільки включає аргументацію, яка пропонує раціональні пояснення емпіричних даних.
Губа, О.
core
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source