Results 51 to 60 of about 92,781 (302)
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Ciência & EducaçãoResumo Este artigo objetiva analisar como alguns grupos da Rede Nacional de Educação e Ciências: Novos Talentos da Rede Pública (RNEC/NT), da região sul do país, operam o que temos chamado discurso pedagógico da ciência em cursos para professores e ...
Lavínia Schwantes +2 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
The Scientific Discourse of Contemporary Humanities. Towards Postmodern De/Normalization (?)
, 2023 This article addresses the latest stage of transformations in Polish scientific discourse, the origins of which are commonly traced back to the 16th century in relation to Polish culture.
Rejter, Artur
core +1 more source
CONCEPT OF CRISIS IN SCIENTIFIC DISCOURSE
Публічне управління та регіональний розвитокThe article examines the main approaches to the concept and content of crisis in scientific literature. The main trends in the development of the crisis and its contradictions are analyzed.
Wang Hong
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Revue d'anthropologie des connaissances, 2010 This presentation connects the developments of Science Studies to those of scientific discourse analysis. Science Studies has come to pay more attention to the concrete situations in which science is elaborated in the laboratory, which is a kind of ...
Francis Grossmann
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Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
SCIENTIFIC AND RELIGIOUS UNIVERSES OF DISCOURSE
Zygon, 1982 . The author argues, by analyzing the logic implicit in scientific and religious statements, that these two kinds of statements belong to different universes of discourse.
doaj +2 more sources