Results 61 to 70 of about 92,781 (302)

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

THE DISCOURSE OF THE EPISTEMIC COMMUNITY OF ARTISTIC GYMNASTICS: THE ANALYSIS OF ARTICLES' TITLES

open access: yesScience of Gymnastics Journal, 2009
The goal of this study was to analyse 105 titles of articles published in 43 journals that are indexed in at least one of the three databases - ScienceDirect, MEDLINE and Scopus - in order to describe the epistemic community that deals with gymnastics ...
Darija Omrčen   +1 more
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Role and position of scientific voices: reported speech in the media

open access: yes, 2003
The purpose of this study is twofold: one, to determine the presence and function of scientific knowledge when it is required by such cases as "mad cows" disease, when the crisis breaks in the press; and two, to explore the role of scientific ...
Calsamiglia, Helena   +1 more
core   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Mitigation in the Scientific Discourse

open access: yesJournal of History Culture and Art Research, 2018
The article is devoted to the study of mitigation strategies and tactics in scientific discourse on the material of English, German and Russian languages. Objectivity, accuracy, consistency and clarity of presentation are traditionally distinguished as the main style-forming factors of scientific discursive practice focused on scientific knowledge.
Darya Abuzyarova, Svetlana Takhtarova
openaire   +2 more sources

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

La profesionalización del artículo científico en España vista desde la evidencialidad = Professionalization of scientific articles in Spain. A study based on the expression of evidentiality

open access: yesEstudios Humanísticos. Filología, 2018
Este artículo ofrece datos sobre la evolución de los artículos científicos en España entre 1799 y 1923 a partir de un estudio exploratorio de la expresión de la evidencialidad: una categoría semántico-pragmática responsable de introducir fuentes de ...
Dorota Kotwica
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

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