Results 151 to 160 of about 17,660,936 (332)

Evaluation of the scientific production of countries by a resource-scaled two-dimensional approach [PDF]

, 2014
Seyyed MehdiHosseini Jenab, Ammar Nejati
openalex   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Certification and potential future use of the reference standard designed for the test system for determination of the fractional (antigenic) composition of human serum products by immunoelectrophoresis

Биопрепараты: Профилактика, диагностика, лечение, 2018
The article gives an account of certification performed for a new batch of a Reference standard to be used with the test system for determination of the fractional (antigenic) composition of human serum products by immunoelectrophoresis -industry ...
O. G. Kornilova, I. L. Arefyeva, E. S. Konovalova, R. A. Volkova, O. V. Fadeykina, E. Yu. Kudasheva, A. A. Movsesyants   +6 more
doaj  

An integrative review of scientific analysis and application on Hyegang Choi Han-Ki’s human-evaluation theory -The relationships between human-evaluation and self-regulation variables in smart -phone addiction scale-

, 2015
moon man ki, JahngSurngGahb
openalex   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Inhibitors of sodium-glucose cotransporter 2: risk of ketoacidosis

Безопасность и риск фармакотерапии, 2018
SGLT2 inhibitors form a new class of hypoglycemic drugs. Despite of the pharmacodynamic profile, at the moment the opinion about their safety is controversial. This is due to increased number of reports given by FDA and EMA on the risk of serious adverse
T. M. Bukatina, A. S. Kazakov, N. Yu. Velts, M. A. Darmostukova, E. Yu. Kolesnikova, R. N. Alyautdin, B. K. Romanov   +6 more
doaj  

Apply sound scientific methodology to the evaluation of new medical treatments [PDF]

, 2011
Rachel A. Lindor, Keith D. Lindor
openalex   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Modern approaches to collecting and reporting information on side effects

Безопасность и риск фармакотерапии, 2018
We have prepared this review of the domestic and foreign scientific literature to characterize the different modern approaches to collecting of ADR information.
K. E. Zatolochina, I. I. Snegireva, A. S. Kazakov, E. Yu. Kolesnikova, E. O. Zhuravleva, T. M. Bukatina, M. A. Darmostukova   +6 more
doaj  

Evaluating the Generalizability and Reproducibility of Scientific Research [PDF]

, 2022
Sue S. Yom, Curtiland Deville, Marjan Boerma, David Carlson, Salma K. Jabbour, Lisa C. Braverman   +5 more
openalex   +1 more source