Results 131 to 140 of about 1,477,560 (316)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

An Evaluation of End-User Interfaces of Scientific Workflow Management Systems

open access: yes, 2005
Scientific research is often exploratory in nature. As technology advances, more steps of such work may become automated. Data used and produced in such experiments becomes increasingly complex and heterogeneous.
Bhagwanani, Sangeeta
core  

A Scale for Describing Levels of Confirmation/Replication in Evaluation

open access: yes, 2006
In order to support both the validity and credibility of claims about program or product merit or worth, we often turn to evaluation. There are various ways in which evaluation can be conducted or managed, which themselves have differing levels of ...
Scriven, Michael, Michael Scriven
core   +1 more source

The science of scientific evaluation

open access: yesGMS German Plastic, Reconstructive and Aesthetic Surgery – Burn and Hand Surgery, 2014
GMS German Plastic, Reconstructive and Aesthetic Surgery; 4:Doc07; ISSN 2193 ...
openaire   +3 more sources

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Multi-level DEA Approach in Research Evaluation [PDF]

open access: yes, 2007
It is well known that the discrimination power of DEA models will be diminishing if too many inputs or outputs are used. It is a dilemma if the decision makers want to select comprehensive indicators to present a relatively holistic evaluation using ...
Zhang, Daqun, Liu, Wenbin, Meng, Wei
core  

Studies on Utilizing the Three Famous International Index Systems to Evaluate Scientific Research Level of Higher Learning Institutions

open access: yes, 2010
Science Citation Index (SCI), The Engineering Index (EI) and Index to Scientific & Technical Proceeding (ISTP) are widely accepted and used to evaluate the scientific research level of higher learning institutions by many country's science and ...
Xun Liu   +5 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Livelihoods in Armenia: Evaluation of new economic opportunities for small-scale farmers in Tavush and Vayots Dzor regions [PDF]

open access: yes, 2015
This evaluation is presented as part of the Effectiveness Review Series 2013/14, selected for review under the livelihoods thematic area. This report documents the findings of a quasi-experimental evaluation carried out in April 2014 that sought to ...
Caeyers, Bet, Nairi Quinn, Natalie
core  

Certification of the industry reference standard for the specific activity of «BiVac polio» - live attenuated bivalent oral polio vaccine type 1 and 3

open access: yesБиопрепараты: Профилактика, диагностика, лечение, 2018
The standardization and control of «BiVac polio» (live attenuated bivalent oral polio vaccine type 1 and 3) developed by M. P. Chumakov Institute of Poliomyelitis and Viral Encephalitides of the Russian Academy of Medical Sciences, called for ...
E. V. Karpova   +6 more
doaj  

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