Results 151 to 160 of about 11,994,000 (257)

Rethinking AI Workflows: Guidelines for Scientific Evaluation in Digital Health Companies. [PDF]

JMIR AI
McAlister KL, Gonzales L, Huberty J.
europepmc   +1 more source

Scientific Evaluation of Medicinal Plants Used for the Treatment of Cervicitis (Qorohe- Rahem) in Iranian Traditional Medicine. [PDF]

Iran J Pharm Res, 2019
Nabimeybodi R, Zareshahi R, Tansaz M, Vahid Dastjerdi M, Hajimehdipoor H.   +4 more
europepmc   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Recommended approaches to the scientific evaluation of ecotoxicological hazards and risks of endocrine-active substances. [PDF]

Integr Environ Assess Manag, 2017
Matthiessen P, Ankley GT, Biever RC, Bjerregaard P, Borgert C, Brugger K, Blankinship A, Chambers J, Coady KK, Constantine L, Dang Z, Denslow ND, Dreier DA, Dungey S, Gray LE, Gross M, Guiney PD, Hecker M, Holbech H, Iguchi T, Kadlec S, Karouna-Renier NK, Katsiadaki I, Kawashima Y, Kloas W, Krueger H, Kumar A, Lagadic L, Leopold A, Levine SL, Maack G, Marty S, Meador J, Mihaich E, Odum J, Ortego L, Parrott J, Pickford D, Roberts M, Schaefers C, Schwarz T, Solomon K, Verslycke T, Weltje L, Wheeler JR, Williams M, Wolf JC, Yamazaki K.   +47 more
europepmc   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

Ewha Medical Journal passed the scientific evaluation by PubMed Central and succeeded in being included in DOAJ, but failed to be accepted by Scopus. [PDF]

Ewha Med J
Huh S.
europepmc   +1 more source

Integrated Care for People with Dementia-Results of a Social-Scientific Evaluation of an Established Dementia Care Model. [PDF]

Geriatrics (Basel), 2016
Richter S.
europepmc   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Correction: Aachen smoking cessation and harm reduction (ASCHR) trial study protocol - scientific evaluation of a psychological-telemedical counseling concept for smoking cessation in patients with vascular diseases. [PDF]

BMC Public Health
Scheliga S, Derissen M, Kröger K, Röhrig R, Schomacher L, Schick H, Beckers R, Böhner H, Habel U.   +8 more
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source