Results 61 to 70 of about 606,604 (206)

Intricacies in Steering the Direction of Science

Novation
René von Schomberg’s article (von Schomberg, 2024) makes an invigorating case for the co-responsibility of societal actors to give direction to the pursuit of science.
Lukas Fuchs
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Responses to the critics

Novation
Personal comment on the responses to “Towards a New Ethos of Science or a Reform of the Institution of Science? Merton Revisited and the Prospects of Institutionalizing the Research Values of Openness and Mutual Responsiveness” by René von Schomberg.
René von Schomberg
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Towards a New Ethos of Science or a Reform of the Institution of Science? Merton Revisited and the Prospects of Institutionalizing the Research Values of Openness and Mutual Responsiveness [Special Edition]

Novation
Over the past decade, we have witnessed a gradual and consistent evolution of research practices towards a more open science. This shift has been driven by both internal expectations within the scientific community and external demands from research ...
René von Schomberg
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

“Emergency” multidisciplinary team meeting in cancer: a first feedback from a care team

Journal of Translational Medicine, 2023
Henri-Corto Stoeklé, David Billard, Jaafar Bennouna, Philippe Beuzeboc, Christian Hervé   +4 more
doaj   +1 more source

Back to the roots: reimagining scientific evaluation of research without peer review

Insights: The UKSG Journal
The peer review system, once a noble aspiration, now lags behind the accelerating demands of modern science. This opinion piece calls for a decisive departure from that peer review system and advocates for a return to a more accountable, editorially ...
Malik Sallam
doaj   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

New Beginning for Tellus – An Earth System Science Journal by Scientists for Scientists

Tellus: Series A, Dynamic Meteorology and Oceanography
Tellus, originally founded in the late 1940s by Carl-Gustaf Rossby, is relaunched as a community-driven Earth system science journal managed by research-active scientists.
Ilona Riipinen, Stefano Manzoni, Rodrigo Caballero, James Famiglietti, Fabien Roquet, Carlos Sierra, Bjorn Stevens, Trude Storelvmo, Giulia Vico   +8 more
doaj   +1 more source