Results 61 to 70 of about 8,060,325 (282)

Publication pressure versus scientific integrity

open access: yesJournal of Integrative Medicine and Research
The scientific community is aware of the issue of publication pressure. While scientific authors frequently discuss the topic, it is not equally addressed at all levels within the scientific hierarchy.
Geeta Chand Acharya
doaj   +1 more source

Letting the daylight in: Reviewing the reviewers and other ways to maximize transparency in science

open access: yesFrontiers in Computational Neuroscience, 2012
With the emergence of online publishing, opportunities to maximize transparency of scientific research have grown considerably. However, these possibilities are still only marginally used. We argue for the implementation of (1) peer-reviewed peer review,
Jelte M Wicherts   +3 more
doaj   +1 more source

Stewardship of Integrity in Scientific Communication [PDF]

open access: yesThe Anatomical Record, 2018
ABSTRACTIntegrity in the pursuit of discovery through application of the scientific method and reporting the results is an obligation for each of us as scientists. We cannot let the value of science be diminished because discovering knowledge is vital to understand ourselves and our impacts on the earth.
openaire   +2 more sources

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Fostering integrity in scientific research

open access: yesAcademic Medicine, 1992
The authors trace the history of the now-symbiotic relationship between universities and the scientific enterprise and indicate how remarkable and beneficial this relationship has been. But, at the same time, universities are beset with troubles, many of their own making, and some of their actions are now questioned by the public.
W H, Danforth, D M, Schoenhoff
openaire   +3 more sources

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Feasibility of Rotor Fault Detection from a Fluid Dynamics Perspective

open access: yesJournal of Applied Fluid Mechanics, 2020
The majority of condition monitoring techniques employed today consider the acquisitioning and analysis of structural responses as a means of profiling machine condition and performing fault detection.
S. L. Robbins, P. S. Heyns, J. A. Heyns
doaj  

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

Analysis of Retractions in Nursing from Publications Between 2000 and 2024: A Bibliometric Analysis Using Retraction Watch

open access: yesNursing Reports
There has been a significant increase in scientific publications in recent years, and the nursing field has been no exception. Consequently, the number of publications containing errors that lead to document retractions has also increased.
María Paz Contreras-Muñoz   +3 more
doaj   +1 more source

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