Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Authorship in scientific manuscripts in occupational therapy: a descriptive study
Cadernos Brasileiros de Terapia Ocupacional, 2023 Introduction: The benefits of multiple authorship are undoubted, but sometimes the number of authors is disproportionately greater than the intellectual content.
Miguel-Ángel Talavera-Valverde +1 more
doaj +1 more source
FEBS Letters, EarlyView.Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source
Digital Editing of Early Modern English Handwritten Texts: Handling Scribal Errors and Corrections [PDF]
, 2017 An important philological question is how to edit texts. An edition always entails interpretation of the text and also of the socio-cultural context in which the manuscript was created and used.
Esteban-Segura, Laura
core
Politically Correct Science: Why Johnny Can’t Read Scientific Creationism
, 2006 The playing field is far from level in the contest between Evolutionism and Scientific Creationism. Science faculty with ambitions to move up to larger universities are unlikely to assign readings in Creation Science.
Stinson, Bart J.
core +1 more source
Sofia A. Yanovskaya: The Marxist Pioneer of Mathematical Logic in the Soviet Union [PDF]
, 2019 K. Marx’s 200th jubilee coincides with the celebration of the 85 years from the first publication of his “Mathematical Manuscripts” in 1933. Its editor, Sofia Alexandrovna Yanovskaya (1896–1966), was a renowned Soviet mathematician ...
Kilakos, Dimitris
core +2 more sources
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
The scientific value of Armenian written manuscripts
Conservation Science in Cultural HeritageLanguage plays an important role in the development of any state because it evolves in direct contact with people's thinking, history, culture, and worldview.
Bibigul Zhiyembay +4 more
doaj +1 more source
Peer review and in-depth interviews with publishers as a means of assessing quality of research monographs [PDF]
, 2008 It has often been observed that evaluating scientific activity in the Humanities and in some of the Social Sciences needs to involve a study of monographs, as they are often the preferred mean of publication by scientists in these fields.
Giménez-Toledo, Elea, Román, Adelaida
core
Germline and Somatic DNA Damage Repair Gene Mutations and Overall Survival in Metastatic Pancreatic Adenocarcinoma Patients Treated with FOLFIRINOX [PDF]
, 2018 Purpose: Pancreatic ductal adenocarcinoma (PDAC) is a lethal cancer with lack of predictive biomarkers. We conducted a study to assess DNA damage repair (DDR) gene mutations as a predictive biomarker in PDAC patients treated with FOLFIRINOX ...
Gbolahan, Olumide +8 more
core +1 more source