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This set of lessons is designed to increase students' knowledge, awareness, and curiosity about the process of scientific exploration of Mars. Topics include navigating to Mars, investigating Martian soils and geology, mapping Martian landforms, and ...
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Assimilation of TES data from the Mars Global Surveyor scientifc mapping phase [PDF]
, 2003 The Thermal Emission Spectrometer (TES)aboard Mars Global Surveyor has produced data which cover almost two Martian years so far (during its scientific mapping phase).
Conrath, Barney J. +5 more
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Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
LandSoil erosion is a pressing global environmental challenge that threatens ecosystem stability, water quality, and biodiversity. While much research has focused on agricultural landscapes, erosion processes within protected areas have received ...
Sai-Leung Ng, Nien-Ming Hong
doaj +1 more source
بازیابی دانش و نظامهای معنایی, 2020 Scientometrics is one of the most important scales for evaluating scientific products that are used to describe scientific studies in terms of their growth, structure, and interactions. The present study was conducted using a scientometrics approach and using co-word analysis and social network analysis (SNA) to investigate relationships in the field ...
Ali Asghar Sadabadi +2 more
openaire +1 more source
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Genetical genomics dissection of cotton fiber quality [PDF]
, 2008 Cotton fiber is a commodity of key economic importance in both developed and developing countries. The two cultivated species, Gossypium hirsutum and G. barbadense , are tetraploid (2n=1x= 52 . 2.3 Gb).
Jacobs, John +2 more
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Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source