Results 91 to 100 of about 36,943,093 (318)

Early research on anther‐smut disease: A fuller view of science?

Ecology and Evolution
The anther‐smut host–pathogen system has provided extensive insights into the evolutionary ecology of disease resistance, transmission modes, host shifts, pathogen specialization, and disease evolution in metapopulations.
Janis Antonovics, Helen M. Alexander
doaj   +1 more source

Historico-Philosophical Aspects of Mathematisation of Nature in Modern Science

Дискурс, 2019
Introduction. The paper deals with the philosophical problems of the mathematisation of nature in modern science.Methodology and sources. The analysis is based on the issues in modern science viewed through the prism of the critique of the ...
A. V. Nesteruk, A. V. Soldatov
doaj   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Sticky Rationality

Politikon, 2015
This essay explores the assumption of rationality in Foreign Policy Analysis. Two approaches, neoclassical realism and schema theory, will be highlighted and it will be examined how they incorporate the notion of rationality. Neoclassical realism reacts
Hans Rusinek
doaj   +1 more source

Rational Choice, Scientific Method and Social Scientism [PDF]

The eighteenth-century introduction of the scientific method of the natural sciences to the study of social phenomena draws a line between moral philosophy Ethat aspect of ancient and medieval philosophy that dealt with social issues Eand the social ...
Bongo Adi, Kenneth Amaeshi, Suminori Tokunaga   +2 more
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Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

ON THE TRANSDISCIPLINARY NATURE OF THE EPISTEMOLOGY OF DISCOVERY

Zygon, 1991
. Despite the by now historical tendency to demarcate scientific epistemology sharply from virtually all others, especially theological “epistemology,” it has recently been recognized that both enterprises share a great deal in common, at least as far ...
doaj   +2 more sources

Leonardo da Vinci – The Scientist

Substantia, 2019
To celebrate the 500th anniversary of Leonardo’s death we gladly republish, with permission, one chapter from Walter Isaacson’s book “Leonardo da Vinci” by Simon & Schuster. Leonardo was born as a natural child on April 15, 1452 in Anchiano, a handful of
Walter Isaacson
doaj   +1 more source

The Valuation of Contaminated Land [PDF]

This paper presents a Monte Carlo based method for explicitly accounting for uncertainty in the valuation of contaminated property. Environmental risk is being quantified by the scientific methods described in this paper.
Bruce R. Weber
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