Results 111 to 120 of about 36,943,093 (318)

LEVELS OF ANALYSIS IN PHILOSOPHY, RELIGION, AND SCIENCE

open access: yesZygon, 2015
This article introduces a model of levels of analysis applied to statements found in philosophical, scientific, and religious discourses in order to facilitate a more accurate description of the relation between science and religion.
doaj   +2 more sources

Identifying and Overcoming Threats to Reproducibility, Replicability, Robustness, and Generalizability in Microbiome Research

open access: yesmBio, 2018
The “reproducibility crisis” in science affects microbiology as much as any other area of inquiry, and microbiologists have long struggled to make their research reproducible. We need to respect that ensuring that our methods and results are sufficiently
Patrick D. Schloss
doaj   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

CONCILIATION, CONFLICT, OR COMPLEMENTARITY: RESPONSES TO THREE VOICES IN THE HINDUISM AND SCIENCE DISCOURSE

open access: yesZygon, 2012
This essay is a response to three review articles on two recently published books dealing with aspects of Hinduism and science: Jonathan Edelmann's Hindu Theology and Biology: The Bhāgavata Purāṇa and Contemporary Theory, and my own, Hindu Perspectives ...
doaj   +2 more sources

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Lost in the woods: Finding our way back to the scientific method in systematic review. [PDF]

open access: yesGlob Epidemiol, 2022
Lynch HN   +3 more
europepmc   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser   +14 more
wiley   +1 more source

Introdução ao método de Pierre Bourdieu

open access: yesCadernos de Campo, 2012
The aim of the following work is to perform a reflection about the research methodology applied and spread by Pierre Bourdieu during his career. Starting from a bibliographical compilation, we shall approach some fundamental concepts to those who seek to
Natalia Scartezini
doaj  

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