Results 81 to 90 of about 4,444,969 (268)
FEA modeling of orthogonal cutting of steel: a review [PDF]
, 2012 Orthogonal cutting is probably the most studied machining operation for metals. Its simulation with the Finite Element Analysis (FEA) method is of paramount academic interest.
Borzan, Marian +3 more
core +1 more source
On model selection criteria for climate change impact studies
, 2018 Climate change impact studies inform policymakers on the estimated damages of future climate change on economic, health and other outcomes. In most studies, an annual outcome variable is observed, e.g.
Cui, X +3 more
core +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Shoulder Range of Motion Measurements and Baseball Elbow Injuries: Ambiguity in Scientific Models, Approach, and Execution is Hurting Overhead Athlete Health. [PDF]
Arthrosc Sports Med Rehabil, 2023 Bullock GS +9 more
europepmc +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Quantum Information Dynamics and Open World Science [PDF]
, 2007 One of the fundamental insights of quantum mechanics is that complete knowledge of the state of a quantum system is not possible. Such incomplete knowledge of a physical system is the norm rather than the exception. This is becoming increasingly apparent
Bruza, Peter, Widdows, Dominic
core +1 more source
Belief Revision in Science: Informational Economy and Paraconsistency [PDF]
, 2017 In the present paper, our objective is to examine the application of belief revision models to scientific rationality. We begin by considering the standard model AGM, and along the way a number of problems surface that make it seem inadequate for this ...
Coimbra, Daniel
core
NNVA: Neural Network Assisted Visual Analysis of Yeast Cell Polarization Simulation
, 2019 Complex computational models are often designed to simulate real-world physical phenomena in many scientific disciplines. However, these simulation models tend to be computationally very expensive and involve a large number of simulation input parameters
Chou, Ching-Shan +4 more
core +1 more source
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Science 3.0: Corrections to the Science 2.0 paradigm [PDF]
, 2013 The concept of Science 2.0 was introduced almost a decade ago to describe the new generation of online-based tools for researchers allowing easier data sharing, collaboration and publishing.
Teif, Vladimir B.
core +1 more source