Results 91 to 100 of about 8,311,638 (299)
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Scientific Research and Growth Volatility [PDF]
This article uncovers a strong link between scientific and engineering publications on the one hand, and growth volatility on the other: growth volatility is significantly lowered by a country’s ability to publish more scientific and engineering journal ...
Sam Tang
core
Overview of science communication (2017-2022): A thematic and bibliographic analysis
Communication & Society (Formerly Comunicación y Sociedad)This article presents the results of an integrative of the literature review on science communication. The objective is to know the panorama of R+D+i in science communication during 6 years; for this purpose, the existing literature on scientific ...
Macarena Parejo-Cuéllar +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
ePESSTO+: survey and scientific output
, 2019 Gathering the ESO community working on supernovae and unusual transients into one coherent team, the Public ESO Spectroscopic Survey of Transient Objects (PESSTO) has revolutionised the exploitation of wide-field surveys, developing efficient synergies with multi-messenger experiments and making the NTT a crucial global facility.
openaire +2 more sources
An index to quantify an individual's scientific research output [PDF]
Proceedings of the National Academy of Sciences, 2005 I propose the index h , defined as the number of papers with citation number ≥ h , as a useful index to characterize the scientific output of a researcher.
openaire +4 more sources
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Quality assessment of scientific outputs using the BWM [PDF]
Scientometrics, 2017 Assessing the quality of scientific outputs (i.e. research papers, books and reports) is a challenging issue. Although in practice, the basic quality of scientific outputs is evaluated by committees/peers (peer review) who have general knowledge and competencies.
openaire +4 more sources
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source