Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
Molecular Oncology, EarlyView.We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source
Iran and Malaysia Scientific Collaboration: a review of co-authorship patterns as reflected in Web of Science [PDF]
تحقیقات کتابداری و اطلاعرسانی دانشگاهی, 2009 Objective: To determine the scope and extent of scientific cooperation between Iran and Malaysia for the 1975-2008 periods. Methodology: A scientometric method was employed covering the collaboration trend with respect to first authors, other ...
Fershte Didegah +1 more
doaj
Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma
Molecular Oncology, EarlyView.Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara +10 more
wiley +1 more source
New approach to the visualization of international scientific collaboration [PDF]
, 2010 In this study, visual representations are created in order to analyze different aspects of scientific collaboration at the international level. The main objective is to identify the international facet of research by following the flow of knowledge as ...
Hassan-Montero, Yusef +4 more
core
Professor Adam Zając — a sketch on His scientific output on the 70th birthday
, 2010 Professor Adam Zając — a sketch on His scientific output on the 70th ...
Bogdan Jackowiak, Waldemar Żukowski
core +1 more source
Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer
Molecular Oncology, EarlyView.New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau +9 more
wiley +1 more source
Dataset for the paper Lotka’s law for the Brazilian scientific output published in journals
, 2018 Dataset for the paper Lotka’s law for the Brazilian scientific output published in ...
Marcelo Perlin (4439659)
core +1 more source
Attitudes of cancer patients toward ctDNA‐based liquid biopsy for follow‐up
Molecular Oncology, EarlyView.This mixed‐methods study explored cancer patients' experiences, knowledge, and preferences regarding ctDNA‐based liquid biopsy for follow‐up. Awareness of ctDNA was low and recall of previous liquid biopsy was imperfect, yet acceptance was high.
Siddharth Chhajlani +7 more
wiley +1 more source
Journal of Nature and Science of MedicinePurpose: The purpose of the study was to evaluate the scientific contribution of King Saud University (KSU) to the field of ophthalmology using bibliometric methods and to contextualize its output within the Arab region.
Majed S. Alkharashi +2 more
doaj +1 more source
The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection
Molecular Oncology, EarlyView.Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński +12 more
wiley +1 more source