Results 81 to 90 of about 9,610,808 (253)

Análisis bibliométrico de la producción y colaboración científica en Oriente Próximo (1998-2007) Bibliometric analysis of sceintific production and collaboration in the middle east from 1998 to 2007

open access: yesInvestigación Bibliotecológica: Archivonomía, Bibliotecología e Información, 2010
Se presenta un análisis bibliométrico de los países de Oriente Próximo a lo largo del período 1998-2007, centrando el análisis en tres aspectos principales (producción, áreas temáticas y colaboración científica), por medio de Web of Science (WoS) y ...
Enrique Orduña-Malea   +2 more
doaj  

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

Mapping the Thematic Network of Humanities Research Output Evaluation: A Mixed Method [PDF]

open access: yesپژوهشنامه علم سنجی
Purpose: Evaluating the outputs of the humanities has always been a fundamental challenge in scientific systems and research policy-making. Unlike empirical sciences, which often rely on quantitative and tangible criteria and indicators to assess their ...
Elahe Ebrahimi Dorcheh, Ali Mansouri
doaj   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

Immersive Investigation of Scientific Data

open access: yes, 2022
Scientific visualization systems normally use keyboard or mouse as input devices and desktop screens or printers/plotters for output. virtual Environment systems, on the other hand, use devices like glove or head mounted display and a number of software ...
Dai, F.   +3 more
core   +1 more source

Overview of science communication (2017-2022): A thematic and bibliographic analysis

open access: yesCommunication & Society (Formerly Comunicación y Sociedad)
This article presents the results of an integrative of the literature review on science communication. The objective is to know the panorama of R+D+i in science communication during 6 years; for this purpose, the existing literature on scientific ...
Macarena Parejo-Cuéllar   +2 more
doaj   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

open access: yesMolecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim   +11 more
wiley   +1 more source

Faculty staff scientific output management

open access: yes, 2009
В статье дана классификация показателей продуктивности научной деятельности, составлен перечень критериев, которым должны удовлетворять такие показатели, выполнен анализ используемого в России показателя результативности научной деятельности, показана ...
Котляров, И. Д.   +1 more
core  

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

open access: yesMolecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir   +9 more
wiley   +1 more source

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

open access: yesMolecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan   +8 more
wiley   +1 more source

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