Results 51 to 60 of about 9,610,808 (253)
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Validation of continuous cardiac output technologies: consensus still awaited. [PDF]
, 2009 An ability to measure cardiac output in a continuous and non-invasive fashion is eagerly awaited in the field of intensive care practice. Modern technologies purport to be able to do this, but the design of studies that validate the manufacturers' claims
Rhodes, A, Cecconi, M
core +1 more source
Target values of input and output of scientific research in non-DEA-effective universities.
, 2023 Target values of input and output of scientific research in non-DEA-effective universities.
Wei Si (579217) +3 more
core +1 more source
O-Index as a New Assessment Index for Citations
Journal of Mazandaran University of Medical Sciences, 2019 Background and purpose: There are some strengths and weaknesses in current indicators of scientometrics. This study aimed to present a new index of scientometrics in evaluating scientific output of Iranian medical journals.
Zahra Foroughi +2 more
doaj
Scientometric Analysis of Digital Ethics in Scopus Database [PDF]
کتابداری و اطلاعرسانیObjective: Considering the role of ethical issues in virtual space, this study has investigated the scientific publications on digital ethics and related fields based on scientometric indicators in Scopus database.Methodology: This research is an applied
Narjes Vara +2 more
doaj +1 more source
The Covid-19 Pandemic and the Global Value of Companies in Emerging Economy Countries [PDF]
Ovidius University Annals: Economic Sciences Series, 2022 The COVID -19 pandemic that broke out in 2019 in China has impacted the economic growth and economic sustainability of all economies of the world. The effects of this health crisis were generally felt by the private sector, which faced a bottleneck in ...
Anatol Melega +2 more
doaj
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Global trends in research resources and scientific output in microbiology in Spain (1998-2007) [PDF]
, 2008 This work assesses the main features of microbiological research developed in Spain over the last decade (1998–2007), observing its changes and trends along the time and comparing them to those which have taken place in other life sciences. This analysis
Arguimbau, Llorenç
core +1 more source
Revista Chilena de Historia Natural, 2010 Hirsch propuso en 2005 el índice-h, el cual integra en un número el impacto de la productividad científica de un investigador, considerando tanto la cantidad de artículos publicados como las citas recibidas. Se ha demostrado que el número de coautores de
MARCO A MOLINA-MONTENEGRO +1 more
doaj