Results 91 to 100 of about 6,086,830 (296)

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Iranian scientific outputs in the field of energy and fuel, and their comparison with those of the Middle East countries [PDF]

مجله علم‌سنجی کاسپین, 2018
Background and aim: Today, the quantitative and qualitative research on the scientific outputs of various fields has been considered in universities and scientific centers.
Mohsen Fazeli varzaneh, Mahdi Bahmani, Erfan Ghaderi Azad   +2 more
doaj  

Scientific collaboration of authors in Payesh Journal from 2012-2019 [PDF]

مجله علم‌سنجی کاسپین, 2020
Background and aim: Scientific collaboration among medical authors is growing. Due to the role of scientific collaboration in improvement of quality and quantity of scientific outputs, the aim of this study was to reflect the scientific collaboration ...
Amrollah Shamsi, Hadiseh Heidari, Zohreh Chanbari   +2 more
doaj  

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

The International Commission on Continental Erosion (ICCE): a brief overview of its scientific focus and example outputs [PDF]

Erosion and sediment-related problems are well documented globally and continue to warrant further scientific investigation, as well as improved policies and management strategies to protect soil and water resources.
Walling, D. E., Walling, Des E., Gellis, Allen C., Golosov, V., da Silva, Yuri Jaques, Porto, P., Chalov, Sergey, Gellis, A. C., Collins, A. L., Silva, Y. J. D., Chalov, S., Golosov, Valentin, Collins, Adrian L., Porto, Paolo   +13 more
core   +1 more source

Mapping the Scientific Outputs of Allameh Tabataba'i University from 1974 to 2024 [PDF]

بازیابی دانش و نظام‌های معنایی
IntroductionScientific outputs that report on the findings of scientific research play a crucial role in enhancing knowledge, advancing science, and promoting research within academic communities.
Seyed Mahdi Taheri, Negin Shokrzadeh
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Outputs and Inputs of Philippine Commercial Banks [PDF]

Exactly what constitutes bank input and output has not yet been settled. Some argue that deposit liabilities and earning assets are outputs as they represent the capacity of services banks can perform.
Lamberte, Mario B.
core  

Outputs / Publications

, 2022
Scientific outputs and publications associated with the project ...
Jonas Obleser, Julia Erb, AC Admin, Sarah Tune, Mohsen Alavash, Leonhard Waschke   +5 more
core   +2 more sources