Results 81 to 90 of about 147,534 (264)
Global scientific outputs of extracorporeal membrane oxygenation in COVID-19: A bibliometric overview. [PDF]
Perfusion, 2023 Kosovali BD, Mutlu NM.
europepmc +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Presenting A Paradigm Model for the Effect of Educational and Research Interactions Between Faculty Members, Students, and Librarians on Scientific Outputs Using a Grounded Theory Approach [PDF]
نشریه مطالعات دانشپژوهیPurpose: This study aimed to develop a model illustrating the impact of research interactions among faculty members, students, and librarians on scientific outputs, employing a grounded theory approach.Methodology: This qualitative research utilized a ...
Safiyeh tahmasebi Limooni
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
ePESSTO+: survey and scientific output
, 2019 Gathering the ESO community working on supernovae and unusual transients into one coherent team, the Public ESO Spectroscopic Survey of Transient Objects (PESSTO) has revolutionised the exploitation of wide-field surveys, developing efficient synergies with multi-messenger experiments and making the NTT a crucial global facility.
openaire +2 more sources
An index to quantify an individual's scientific research output [PDF]
Proceedings of the National Academy of Sciences, 2005 I propose the index h , defined as the number of papers with citation number ≥ h , as a useful index to characterize the scientific output of a researcher.
openaire +3 more sources
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source