Results 81 to 90 of about 6,086,830 (296)

Exploring Scientific Outputs about Globalization: A Conceptual Framework Study [PDF]

open access: yesجامعه شناسی کاربردی
IntroductionBibliometric analysis is widely acknowledged as a robust and systematic approach for examining extensive scholarly literature. It serves as a vital tool for mapping the landscape of contemporary research across various academic fields.
Saleh Rahimi, Faramarz Soheili
doaj   +1 more source

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

open access: yesFEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

Scientific Publication Packages – A Selective Approach to the Communication and Archival of Scientific Output [PDF]

open access: yesInternational Journal of Digital Curation, 2008
The use of digital technologies within research has led to a proliferation of data, many new forms of research output and new modes of presentation and analysis. Many scientific communities are struggling with the challenge of how to manage the terabytes of data and new forms of output, they are producing.
openaire   +10 more sources

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Assessing graduate screen production outputs in nineteen Australian film schools [PDF]

open access: yes, 2011
The project addresses the question: can the output of creative practices, such as screen production, be measured or is it in the eye of the beholder? The aim of the project was to accumulate a body of evidence to demonstrate that evaluation of creative ...
Petkovic, J.   +5 more
core  

A comparative study on the scientific outputs of agricultural faculty members at State Universities in Khuzestan [PDF]

open access: yesمجله علم‌سنجی کاسپین, 2018
Background and aim: Today, the scientific outputs of universities are quantitatively and qualitatively measured using scientometrics on which the scientific progress of these institutions is evaluated.
Zahed Bigdeli   +2 more
doaj  

Iranian scientific outputs before and after the initiation of Scientometrics: A short communication [PDF]

open access: yesمجله علم‌سنجی کاسپین, 2021
Background and aim: Scientometrics as a system of scientific communication plays an important role in evaluating, policy-making and future developments in scientific outputs.
Mousa Bamir   +2 more
doaj  

Evaluation of scientific output in Dentistry in Spanish Universities

open access: yesMedicina Oral Patología Oral y Cirugia Bucal, 2017
The aim of this study was to assess the scientific output of Spanish universities that offer a bachelor's degree in dentistry through the use of various bibliometric indicators.A total of 21 universities offered a bachelor's degree in dentistry in academic year 2016-2017. The search for papers published by authors associated with these institutions was
Flor Martínez, María De la   +5 more
openaire   +5 more sources

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