Results 121 to 130 of about 958,595 (253)

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Communicating science: a responsibility on par with scientific practice. [PDF]

Arq Bras Oftalmol
Santhiago MR.
europepmc   +1 more source

Better Practices in Scientific Publishing [PDF]

Angewandte Chemie International Edition, 2016
openaire   +2 more sources

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Practical measures for achieving greater alignment between scientific practice and meaningful research output. [PDF]

Biophys Rev
Hall D.
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Reply to Krefeld-Schwalb et al.: Measuring population heterogeneity requires upholding good scientific practice. [PDF]

Proc Natl Acad Sci U S A
Holzmeister F, Johannesson M, Böhm R, Dreber A, Huber J, Kirchler M.   +5 more
europepmc   +1 more source

The scientific evidence and clinical practice

Medwave, 2014
openaire   +3 more sources

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Dissemination of clinical and scientific practice through social media: a SIAARTI consensus-based document. [PDF]

J Anesth Analg Crit Care
Cortegiani A, Battaglini D, Amato G, Behr AU, Donadello K, Einav S, Frigo MG, Fullin G, Giannini A, Ippolito M, Marozzi F, Monzani R, Monti G, Schultz MJ, Torrano V, Villa G, Giarratano A.   +16 more
europepmc   +1 more source